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LHX5 LIM homeobox 5 [ Gallus gallus (chicken) ]

Gene ID: 771259, updated on 17-Aug-2024

Summary

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Symbol
LHX5provided by CGNC
Full Name
LIM homeobox 5provided by CGNC
Primary source
CGNC:6292
See related
Ensembl:ENSGALG00010000445
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See LHX5 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
6
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (12575498..12583138)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (12587668..12595313)

Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene RNA binding motif protein 19 Neighboring gene uncharacterized LOC124417238 Neighboring gene serine dehydratase like Neighboring gene phospholipase B domain containing 2 Neighboring gene solute carrier family 8 member B1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The expression of LIM-homeobox genes, Lhx1 and Lhx5, in the forebrain is essential for neural retina differentiation. Inoue J, et al. Dev Growth Differ, 2013 Sep. PMID 24024588
  2. Lhx1 in the proximal region of the optic vesicle permits neural retina development in the chicken. Kawaue T, et al. Biol Open, 2012 Nov 15. PMID 23213388, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LIM/homeobox protein Lhx5
Names
LIM homeobox protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001320906.1 → NP_001307835.1  LIM/homeobox protein Lhx5

    Status: PROVISIONAL

    Source sequence(s)
    AB485718
    UniProtKB/TrEMBL
    A0A140JTJ9, A0A8V0X5B1, E1BQX0
    Related
    ENSGALP00010000493.1, ENSGALT00010000929.1
    Conserved Domains (3) summary
    cd09367
    Location:5 → 56
    LIM1_Lhx1_Lhx5; The first LIM domain of Lhx1 (also known as Lim1) and Lhx5
    cd09375
    Location:64 → 119
    LIM2_Lhx1_Lhx5; The second LIM domain of Lhx1 (also known as Lim1) and Lhx5
    pfam00046
    Location:183 → 237
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    12575498..12583138
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004934489.5 → XP_004934546.1  LIM/homeobox protein Lhx5 isoform X1

    Conserved Domains (3) summary
    cd09367
    Location:5 → 56
    LIM1_Lhx1_Lhx5; The first LIM domain of Lhx1 (also known as Lim1) and Lhx5
    cd09375
    Location:64 → 119
    LIM2_Lhx1_Lhx5; The second LIM domain of Lhx1 (also known as Lim1) and Lhx5
    pfam00046
    Location:183 → 236
    Homeobox; Homeobox domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    12587668..12595313
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046928268.1 → XP_046784224.1  LIM/homeobox protein Lhx5 isoform X1

Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials