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THAPSDRAFT_263816 chromodomain-helicase [ Thalassiosira pseudonana CCMP1335 ]

Gene ID: 7444484, updated on 21-Dec-2023

Summary

Gene symbol
THAPSDRAFT_263816
Gene description
chromodomain-helicase
Locus tag
THAPSDRAFT_263816
Gene type
protein coding
RNA name
chromodomain-helicase
RefSeq status
PROVISIONAL
Organism
Thalassiosira pseudonana CCMP1335 (strain: CCMP1335)
Lineage
Eukaryota; Stramenopiles; Bacillariophyta; Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales; Thalassiosiraceae; Thalassiosira
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Genomic context

See THAPSDRAFT_263816 in Genome Data Viewer
Location:
chromosome: 11, map: unlocalized
Exon count:
10

NW_002243504.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Names
chromodomain-helicase
XP_002296471.1
  • The CHROMO (CHRromatin Organization MOdifier) domain is a conserved region of around 60 amino acids, originally identified in Drosophila modifiers of variegation. These are proteins that alter the structure of chromatin to the condensed morphology of heterochromatin, a cytologically visible condition where gene expression is repressed. In one of these proteins, Polycomb, the chromo domain has been shown to be important for chromatin targeting. Proteins that contain a chromo domain appear to fall into 3 classes. The first class includes proteins having an N-terminal chromo domain followed by a region termed the chromo shadow domain, eg. Drosophila and human heterochromatin protein Su(var)205 (HP1); and mammalian modifier 1 and modifier 2. The second class includes proteins with a single chromo domain, eg. Drosophila protein Polycomb (Pc); mammalian modifier 3; human Mi-2 autoantigenand and several yeast and C. elegans hypothetical proteins. In the third class paired tandem chromo domains are found, eg. in mammalian DNA-binding/helicase proteins CHD-1 to CHD-4 and yeast protein CHD1.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NW_002243504.1 Reference assembly

    Range
    662591..667199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002296435.1XP_002296471.1  chromodomain-helicase, partial [Thalassiosira pseudonana CCMP1335]

    See identical proteins and their annotated locations for XP_002296471.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    B8LC70
    Conserved Domains (4) summary
    cd00046
    Location:92257
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00176
    Location:75379
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:421535
    Helicase_C; Helicase conserved C-terminal domain
    pfam00385
    Location:126
    Chromo; Chromo (CHRromatin Organization MOdifier) domain