aldh1a2 aldehyde dehydrogenase 1 family member A2 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: aldh1a2provided by Xenbase
Official Full Name: aldehyde dehydrogenase 1 family member A2provided by Xenbase
Primary source: Xenbase:XB-GENE-1012909
See related: Ensembl:ENSXETG00000010865 AllianceGenome:Xenbase:XB-GENE-1012909
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: raldh2; XRaldh2; raldh-2; raldh2-t; raldh(ii)
Summary: Predicted to enable oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in congenital diaphragmatic hernia. Orthologous to human ALDH1A2 (aldehyde dehydrogenase 1 family member A2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	3	NC_030679.2 (99573657..99607654)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	3	NC_030679.1 (89622828..89656127)

Chromosome 3 - NC_030679.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development.
Title: Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development.

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: retinal dehydrogenase 2

NP_001039196.1

EC 1.2.1.36

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.