msgn1 mesogenin 1 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: msgn1provided by Xenbase
Official Full Name: mesogenin 1provided by Xenbase
Primary source: Xenbase:XB-GENE-972085
See related: Ensembl:ENSXETG00000015571 AllianceGenome:Xenbase:XB-GENE-972085
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: mes1; msog; Mespo; msgn1-a; msgn1-b; mesogenin; pMesogenin1
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in mesoderm formation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cell differentiation. Predicted to be active in nucleus. Orthologous to human MSGN1 (mesogenin 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	5	NC_030681.2 (141934598..141935533)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	5	NC_030681.1 (137752741..137753676)

Chromosome 5 - NC_030681.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in mesoderm formation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mesogenin-1

Names: MesP-related bHLH factor; mesogenin, Mespo MesP-related bHLH factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001045639.1 → NP_001039104.1 mesogenin-1

See identical proteins and their annotated locations for NP_001039104.1

Status: PROVISIONAL

Source sequence(s)

CR942397

UniProtKB/Swiss-Prot

Q28C89

UniProtKB/TrEMBL

B4F6H6

Related

ENSXETP00000033971.3, ENSXETT00000033971.5

Conserved Domains (1) summary

cd18939
Location:102 → 167

bHLH_TS_Msgn1; basic helix-loop-helix (bHLH) domain found in mesogenin-1 (Msgn1) and similar proteins