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nin.L ninein L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 733210, updated on 4-Nov-2024

Summary

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Official Symbol
nin.L
Official Full Name
ninein L homeolog
Primary source
Xenbase:XB-GENE-954255
Locus tag
XELAEV_18039678mg
See related
EnsemblRapid:ENSXLAG00005019582 AllianceGenome:Xenbase:XB-GENE-954255
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
nin
Summary
Predicted to enable calcium ion binding activity. Predicted to act upstream of or within centrosome localization; centrosome-templated microtubule nucleation; and microtubule anchoring at centrosome. Predicted to be located in cytoplasm and microtubule cytoskeleton. Predicted to be part of ciliary transition fiber. Human ortholog(s) of this gene implicated in Seckel syndrome 7. Orthologous to human NIN (ninein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nin.L in Genome Data Viewer
Location:
chromosome: 8L
Exon count:
33
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (87245438..87318553)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (72554460..72617487)

Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene phosphorylase, glycogen, liver L homeolog Neighboring gene lysophosphatidylserine lipase ABHD12 Neighboring gene protein kinase domain containing, cytoplasmic, gene 1 L homeolog Neighboring gene echinoderm microtubule associated protein like 1 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within centrosome localization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within centrosome-templated microtubule nucleation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within microtubule anchoring at centrosome IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in centriole IEA
Inferred from Electronic Annotation
more info
  
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
part_of ciliary transition fiber IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in mitotic spindle pole IEA
Inferred from Electronic Annotation
more info
  
located_in pericentriolar material IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ninein; uncharacterized protein LOC733210
Names
ninein (GSK3B interacting protein)
ninein-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    87245438..87318553
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041573056.1 → XP_041428990.1  ninein isoform X2

    UniProtKB/TrEMBL
    A0A8J1LJW3
    Related
    ENSXLAP00005057530.1, ENSXLAT00005058883.1
    Conserved Domains (2) summary
    COG1196
    Location:373 → 1142
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:1698 → 2053
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  2. XM_041573055.1 → XP_041428989.1  ninein isoform X1

    UniProtKB/TrEMBL
    A0A8J1LIT2
    Related
    ENSXLAP00005057526.1, ENSXLAT00005058879.1
    Conserved Domains (1) summary
    COG1196
    Location:373 → 1142
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  3. XM_041573058.1 → XP_041428992.1  ninein isoform X5

    UniProtKB/TrEMBL
    A0A8J1LHI4
    Related
    ENSXLAP00005057518.1, ENSXLAT00005058871.1
    Conserved Domains (2) summary
    COG1196
    Location:373 → 1142
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG4372
    Location:1773 → 1960
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]

  4. XM_018230550.2 → XP_018086039.1  ninein isoform X3

    UniProtKB/TrEMBL
    A0A1L8F9V7, A0A974C873
    Related
    ENSXLAP00005057499.1, ENSXLAT00005058852.1

  5. XM_041573059.1 → XP_041428993.1  ninein isoform X6

    UniProtKB/TrEMBL
    A0A8J1LHE5
    Related
    ENSXLAP00005057547.1, ENSXLAT00005058900.1
    Conserved Domains (2) summary
    COG1196
    Location:424 → 1235
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR04523
    Location:1036 → 1511
    Mplasa_alph_rch; helix-rich Mycoplasma protein

  6. XM_018230551.2 → XP_018086040.1  ninein isoform X7

    UniProtKB/TrEMBL
    A0A8J0TK03, Q52L21
    Related
    ENSXLAP00005057488.1, ENSXLAT00005058841.1

  7. XM_041573057.1 → XP_041428991.1  ninein isoform X4

    UniProtKB/TrEMBL
    A0A8J1LI11
    Conserved Domains (3) summary
    PTZ00121
    Location:472 → 1006
    PTZ00121; MAEBL; Provisional
    COG1196
    Location:859 → 1731
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02169
    Location:229 → 582
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
Nucleotide Protein Strain
Heading Accession and Version

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