U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

runx1t1.L RUNX1 translocation partner 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 733153, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
runx1t1.L
Official Full Name
RUNX1 translocation partner 1 L homeolog
Primary source
Xenbase:XB-GENE-865458
Locus tag
XELAEV_18032184mg
See related
EnsemblRapid:ENSXLAG00005027887 AllianceGenome:Xenbase:XB-GENE-865458
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
runx1t1
Summary
Predicted to enable metal ion binding activity and transcription corepressor activity. Predicted to act upstream of or within DNA-templated transcription and negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in ectoderm; endoderm; and nervous system. Orthologous to human RUNX1T1 (RUNX1 partner transcriptional co-repressor 1). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See runx1t1.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (136734134..136844351, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (127564215..127674937, complement)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 69 L homeolog Neighboring gene solute carrier family 26 (anion exchanger), member 7 L homeolog Neighboring gene uncharacterized LOC121394756 Neighboring gene triple QxxK/R motif containing L homeolog

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The expression and function of MTG/ETO family proteins during neurogenesis. Koyano-Nakagawa N, et al. Dev Biol, 2005 Feb 1. PMID 15649458
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein CBFA2T1
Names
MTG8
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) L homeolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095596.1 → NP_001089065.1  protein CBFA2T1

    See identical proteins and their annotated locations for NP_001089065.1

    Status: PROVISIONAL

    Source sequence(s)
    AY714077
    UniProtKB/TrEMBL
    A0A974HGT2, Q5IJ72
    Related
    ENSXLAP00005083296.1, ENSXLAT00005084932.1
    Conserved Domains (5) summary
    COG1390
    Location:421 → 485
    NtpE; Archaeal/vacuolar-type H+-ATPase subunit E/Vma4 [Energy production and conversion]
    pfam01753
    Location:493 → 529
    zf-MYND; MYND finger
    pfam07531
    Location:102 → 188
    TAFH; NHR1 homology to TAF
    pfam08788
    Location:317 → 383
    NHR2; NHR2 domain like
    cl23750
    Location:419 → 475
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    136734134..136844351 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials