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CD274 CD274 molecule [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716043, updated on 17-Aug-2024

Summary

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Official Symbol
CD274provided by VGNC
Official Full Name
CD274 moleculeprovided by VGNC
Primary source
VGNC:VGNC:70814
Locus tag
EGK_07725
See related
Ensembl:ENSMMUG00000012235
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See CD274 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
6
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (78309994..78330073, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (78974909..78995400, complement)

Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene RIC1 homolog, RAB6A GEF complex partner 1 Neighboring gene programmed cell death 1 ligand 2 Neighboring gene uncharacterized LOC114672797 Neighboring gene uncharacterized LOC114672798 Neighboring gene E3 ubiquitin-protein ligase RNF152-like Neighboring gene plasminogen receptor with a C-terminal lysine

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in T cell costimulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to lipopolysaccharide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of T cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of T cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
programmed cell death 1 ligand 1
Names
programmed cell death ligand 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083889.1 → NP_001077358.1  programmed cell death 1 ligand 1 precursor

    See identical proteins and their annotated locations for NP_001077358.1

    Status: PROVISIONAL

    Source sequence(s)
    EF444814
    UniProtKB/TrEMBL
    A4GW29, A4GW31
    Related
    ENSMMUP00000039207.2, ENSMMUT00000046162.3
    Conserved Domains (2) summary
    smart00410
    Location:24 → 130
    IG_like; Immunoglobulin like
    cl11960
    Location:66 → 114
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041768.1 Reference Mmul_10 Primary Assembly

    Range
    78309994..78330073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015117668.2 → XP_014973154.1  programmed cell death 1 ligand 1 isoform X3

    UniProtKB/TrEMBL
    A0A5F8A285, A0A8J8Y3P9, A4GW31, F6VEW6
    Related
    ENSMMUP00000071043.1, ENSMMUT00000101160.1
    Conserved Domains (2) summary
    smart00410
    Location:24 → 130
    IG_like; Immunoglobulin like
    cl11960
    Location:66 → 114
    Ig; Immunoglobulin domain

  2. XM_015117665.2 → XP_014973151.1  programmed cell death 1 ligand 1 isoform X2

    UniProtKB/TrEMBL
    A4GW31
    Conserved Domains (2) summary
    smart00410
    Location:24 → 130
    IG_like; Immunoglobulin like
    cl11960
    Location:66 → 114
    Ig; Immunoglobulin domain

  3. XM_028834391.1 → XP_028690224.1  programmed cell death 1 ligand 1 isoform X1

    UniProtKB/TrEMBL
    A4GW31
    Conserved Domains (1) summary
    cl11960
    Location:54 → 117
    Ig; Immunoglobulin domain

  4. XM_028834392.1 → XP_028690225.1  programmed cell death 1 ligand 1 isoform X1

    UniProtKB/TrEMBL
    A4GW31
    Conserved Domains (1) summary
    cl11960
    Location:54 → 117
    Ig; Immunoglobulin domain

RNA

  1. XR_003723007.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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Research Materials