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ALOX5AP arachidonate 5-lipoxygenase activating protein [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 713170, updated on 17-Aug-2024

Summary

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Official Symbol
ALOX5APprovided by VGNC
Official Full Name
arachidonate 5-lipoxygenase activating proteinprovided by VGNC
Primary source
VGNC:VGNC:69799
Locus tag
EGK_09217
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
FLAP
Orthologs
human mouse all
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Genomic context

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See ALOX5AP in Genome Data Viewer
Location:
chromosome: 17
Exon count:
5
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (9794390..9819196)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (10304323..10329659)

Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase like 1 Neighboring gene transfer RNA asparagine (anticodon GUU) Neighboring gene uncharacterized LOC106994208 Neighboring gene mesenteric estrogen dependent adipogenesis

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cross-species comparison of 5-lipoxygenase-activating protein. Vickers PJ, et al. Mol Pharmacol, 1992 Dec. PMID 1480129
  2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables enzyme activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glutathione peroxidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glutathione transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables leukotriene-C4 synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in leukotriene biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 5-lipoxygenase-activating protein
Names
5-lipoxygenase-activating protein
MK-886-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266489.1 → NP_001253418.1  arachidonate 5-lipoxygenase-activating protein

    See identical proteins and their annotated locations for NP_001253418.1

    Status: PROVISIONAL

    Source sequence(s)
    JU322430
    UniProtKB/Swiss-Prot
    P30354
    UniProtKB/TrEMBL
    A0A8J8XMD5, G7NJW2, H9EUX7
    Conserved Domains (1) summary
    pfam01124
    Location:9 → 128
    MAPEG; MAPEG family

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041770.1 Reference Mmul_10 Primary Assembly

    Range
    9794390..9819196
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P30354.1 GenPept UniProtKB/Swiss-Prot:P30354

Gene LinkOut

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