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LSS lanosterol synthase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 709227, updated on 17-Aug-2024

Summary

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Official Symbol
LSSprovided by VGNC
Official Full Name
lanosterol synthaseprovided by VGNC
Primary source
VGNC:VGNC:74451
See related
Ensembl:ENSMMUG00000022329
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See LSS in Genome Data Viewer
Location:
chromosome: 3
Exon count:
23
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (556085..595132)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (545428..584499)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene chromosome 3 C21orf58 homolog Neighboring gene uncharacterized LOC114676782 Neighboring gene ybeY metalloendoribonuclease Neighboring gene minichromosome maintenance complex component 3 associated protein Neighboring gene uncharacterized LOC106997207 Neighboring gene uncharacterized LOC106997208 Neighboring gene spermatogenesis and centriole associated 1 like Neighboring gene formimidoyltransferase cyclodeaminase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables lanosterol synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in triterpenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lanosterol synthase
Names
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
XP_014988166.1
XP_028701041.1
XP_028701042.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    556085..595132
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015132680.2 → XP_014988166.1  lanosterol synthase isoform X1

    UniProtKB/TrEMBL
    I2CTH0
    Related
    ENSMMUP00000029398.4, ENSMMUT00000031417.4
    Conserved Domains (2) summary
    cd02892
    Location:77 → 719
    SQCY_1; Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization ...
    TIGR01787
    Location:76 → 721
    squalene_cyclas; squalene/oxidosqualene cyclases

  2. XM_028845208.1 → XP_028701041.1  lanosterol synthase isoform X2

    UniProtKB/TrEMBL
    I2CTH0
    Conserved Domains (1) summary
    TIGR01787
    Location:76 → 694
    squalene_cyclas; squalene/oxidosqualene cyclases

  3. XM_028845209.1 → XP_028701042.1  lanosterol synthase isoform X3

    UniProtKB/TrEMBL
    I2CTH0
    Conserved Domains (1) summary
    TIGR01787
    Location:76 → 607
    squalene_cyclas; squalene/oxidosqualene cyclases
Nucleotide Protein
Heading Accession and Version

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