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PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 707310, updated on 17-Aug-2024

Summary

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Official Symbol
PIK3R3provided by VGNC
Official Full Name
phosphoinositide-3-kinase regulatory subunit 3provided by VGNC
Primary source
VGNC:VGNC:112154
Locus tag
EGK_00708
See related
Ensembl:ENSMMUG00000015080
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PIK3R3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (178258119..178354261)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (45650771..45747395, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene tetraspanin 1 Neighboring gene PIK3R3 upstream open reading frame Neighboring gene 40S ribosomal protein S29 pseudogene Neighboring gene microtubule associated serine/threonine kinase 2 Neighboring gene translation machinery-associated protein 16 pseudogene Neighboring gene intracisternal A particle-promoted polypeptide

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase regulatory subunit gamma
Names
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266826.1 → NP_001253755.1  phosphatidylinositol 3-kinase regulatory subunit gamma

    See identical proteins and their annotated locations for NP_001253755.1

    Status: PROVISIONAL

    Source sequence(s)
    JV048505
    UniProtKB/TrEMBL
    F6WVE5, F7GR36, F7GR38, H9G113
    Related
    ENSMMUP00000070057.1, ENSMMUT00000083859.1
    Conserved Domains (3) summary
    cd09930
    Location:351 → 454
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:59 → 167
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cl25402
    Location:172 → 332
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    178258119..178354261
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015138437.2 → XP_014993923.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2

    UniProtKB/TrEMBL
    F6WVE5, F7GR36, F7GR38, H9G113
    Conserved Domains (3) summary
    cd09930
    Location:351 → 454
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:59 → 167
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cl25402
    Location:172 → 332
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

  2. XM_015138423.2 → XP_014993909.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1

    UniProtKB/TrEMBL
    F6WVE5
    Conserved Domains (3) summary
    cd09930
    Location:368 → 471
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:76 → 184
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12925
    Location:189 → 349
    iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma

  3. XM_015138431.2 → XP_014993917.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2

    UniProtKB/TrEMBL
    F6WVE5, F7GR36, F7GR38, H9G113
    Related
    ENSMMUP00000040267.3, ENSMMUT00000047240.3
    Conserved Domains (3) summary
    cd09930
    Location:351 → 454
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:59 → 167
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cl25402
    Location:172 → 332
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

  4. XM_015138440.2 → XP_014993926.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3

    UniProtKB/TrEMBL
    F6WVD4, F6WVE5
    Related
    ENSMMUP00000019765.4, ENSMMUT00000021139.4
    Conserved Domains (3) summary
    cd09930
    Location:307 → 410
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:15 → 123
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cl25402
    Location:128 → 288
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
Nucleotide Protein
Heading Accession and Version

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