OCRL OCRL inositol polyphosphate-5-phosphatase [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: OCRLprovided by VGNC
Official Full Name: OCRL inositol polyphosphate-5-phosphataseprovided by VGNC
Primary source: VGNC:VGNC:75577
See related: Ensembl:ENSMMUG00000008825
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: X

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	X	NC_041774.1 (125800696..125851524)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	X	NC_027913.1 (123434944..123485766)

Chromosome X - NC_041774.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

G54523 (e-PCR)
- UniSTS:116232

G42864 (e-PCR)
- UniSTS:94773

PMC24149P18 (e-PCR)
- UniSTS:272229

PMC24149P19 (e-PCR)
- UniSTS:272230

PMC24149P20 (e-PCR)
- UniSTS:272232

A006N02 (e-PCR)
- UniSTS:25475

L78118 (e-PCR)
- UniSTS:24207

RH1710 (e-PCR)
- UniSTS:79784

DXS8279 (e-PCR)
- UniSTS:44486

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables inositol phosphate phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in phosphatidylinositol dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: inositol polyphosphate 5-phosphatase OCRL

Names: inositol polyphosphate 5-phosphatase OCRL-1

NP_001252718.1

EC 3.1.3.36

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001265789.1 → NP_001252718.1 inositol polyphosphate 5-phosphatase OCRL

See identical proteins and their annotated locations for NP_001252718.1

Status: PROVISIONAL

Source sequence(s)

JV635564

UniProtKB/TrEMBL

F7EWX0, H9F9F2, I2CVB9

Related

ENSMMUP00000011574.4, ENSMMUT00000012341.4

Conserved Domains (3) summary

cd09093
Location:240 → 533

INPP5c_INPP5B; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins

cd04380
Location:668 → 888

RhoGAP_OCRL1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate 5-phosphatase domain and ...

cd13382
Location:11 → 115

PH_OCRL1; oculocerebrorenal syndrome of Lowe 1 Pleckstrin homology-like domain