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MECP2 methyl-CpG binding protein 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 700174, updated on 17-Aug-2024

Summary

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Official Symbol
MECP2provided by VGNC
Official Full Name
methyl-CpG binding protein 2provided by VGNC
Primary source
VGNC:VGNC:74697
See related
Ensembl:ENSMMUG00000018704
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MECP2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
7
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (150013278..150090459, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (147501300..147577320, complement)

Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 187 Neighboring gene interleukin 1 receptor associated kinase 1 Neighboring gene testis-specific protein TEX28 Neighboring gene opsin 1, long wave sensitive

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded methylated DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methyl-CpG binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of heterochromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
methyl-CpG-binding protein 2
Names
methyl CpG binding protein 2 (Rett syndrome)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257542.1 → NP_001244471.1  methyl-CpG-binding protein 2

    See identical proteins and their annotated locations for NP_001244471.1

    Status: PROVISIONAL

    Source sequence(s)
    JU334548
    UniProtKB/TrEMBL
    A0A1D5R9D1, G7NSK9, H9FUJ2
    Related
    ENSMMUP00000066042.1, ENSMMUT00000089434.1
    Conserved Domains (1) summary
    smart00391
    Location:92 → 169
    MBD; Methyl-CpG binding domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041774.1 Reference Mmul_10 Primary Assembly

    Range
    150013278..150090459 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015128480.2 → XP_014983966.1  methyl-CpG-binding protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R6L5, G7NSK9, I2CX16
    Related
    ENSMMUP00000055953.2, ENSMMUT00000063447.2
    Conserved Domains (1) summary
    smart00391
    Location:104 → 181
    MBD; Methyl-CpG binding domain

  2. XM_028841735.1 → XP_028697568.1  methyl-CpG-binding protein 2 isoform X2

    UniProtKB/TrEMBL
    G7NSK9
    Conserved Domains (1) summary
    smart00391
    Location:1 → 76
    MBD; Methyl-CpG binding domain

  3. XM_015128481.2 → XP_014983967.1  methyl-CpG-binding protein 2 isoform X2

    UniProtKB/TrEMBL
    G7NSK9
    Conserved Domains (1) summary
    smart00391
    Location:1 → 76
    MBD; Methyl-CpG binding domain
Nucleotide Protein
Heading Accession and Version

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