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PLCD1 phospholipase C delta 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 696860, updated on 17-Aug-2024

Summary

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Official Symbol
PLCD1provided by VGNC
Official Full Name
phospholipase C delta 1provided by VGNC
Primary source
VGNC:VGNC:76166
Locus tag
EGK_11798
See related
Ensembl:ENSMMUG00000000985
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PLCD1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
16
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (93445286..93467664, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (104717226..104739568)

Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene CTD small phosphatase like Neighboring gene microRNA mir-26a-1 Neighboring gene villin like Neighboring gene serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform pseudogene Neighboring gene DLEC1 cilia and flagella associated protein Neighboring gene acetyl-CoA acyltransferase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
Names
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
XP_001089399.1
XP_014986841.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041755.1 Reference Mmul_10 Primary Assembly

    Range
    93445286..93467664 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015131355.1 → XP_014986841.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2

    UniProtKB/TrEMBL
    F6VRS9, I0FHZ5
    Related
    ENSMMUP00000080931.1, ENSMMUT00000085235.1
    Conserved Domains (7) summary
    cd00275
    Location:629 → 755
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:295 → 596
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    PLN02228
    Location:212 → 755
    PLN02228; Phosphoinositide phospholipase C
    cd13363
    Location:22 → 139
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    pfam00169
    Location:30 → 130
    PH; PH domain
    pfam09279
    Location:213 → 295
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    pfam14788
    Location:159 → 208
    EF-hand_10; EF hand

  2. XM_001089399.4 → XP_001089399.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

    See identical proteins and their annotated locations for XP_001089399.1

    UniProtKB/TrEMBL
    A0A5F7ZCB2, A0A8J8XPQ2, F6VRS9, G7MJ18
    Related
    ENSMMUP00000063247.1, ENSMMUT00000093771.1
    Conserved Domains (7) summary
    cd00275
    Location:650 → 776
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:316 → 617
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    PLN02228
    Location:233 → 776
    PLN02228; Phosphoinositide phospholipase C
    cd13363
    Location:43 → 160
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    pfam00169
    Location:51 → 151
    PH; PH domain
    pfam09279
    Location:234 → 316
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    pfam14788
    Location:180 → 229
    EF-hand_10; EF hand

RNA

  1. XR_001443060.2 RNA Sequence

Nucleotide Protein
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