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MBTPS2 membrane bound transcription factor peptidase, site 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 696540, updated on 5-Mar-2024

Summary

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Gene symbol
MBTPS2
Gene description
membrane bound transcription factor peptidase, site 2
See related
Ensembl:ENSMMUG00000022467
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MBTPS2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (21612978..21658872)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (21265569..21324121)

Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene small muscle protein X-linked Neighboring gene dnaJ homolog subfamily A member 1 pseudogene Neighboring gene YY2 transcription factor Neighboring gene spermine synthase Neighboring gene phosphate regulating endopeptidase X-linked Neighboring gene uncharacterized LOC114674658

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane protein intracellular domain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
membrane-bound transcription factor site-2 protease
XP_014982566.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041774.1 Reference Mmul_10 Primary Assembly

    Range
    21612978..21658872
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015127080.2 → XP_014982566.1  membrane-bound transcription factor site-2 protease

    UniProtKB/TrEMBL
    G7NSN8
    Related
    ENSMMUP00000029553.3, ENSMMUT00000031589.4
    Conserved Domains (2) summary
    cd06162
    Location:18 → 230
    S2P-M50_PDZ_SREBP; Sterol regulatory element-binding protein (SREBP) Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50A), regulates intramembrane proteolysis (RIP) of SREBP and is part of a signal transduction mechanism involved in sterol and lipid ...
    pfam02163
    Location:160 → 501
    Peptidase_M50; Peptidase family M50
Nucleotide Protein
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