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Gal3st1 galactose-3-O-sulfotransferase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 683713, updated on 14-Nov-2024

Summary

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Official Symbol
Gal3st1provided by RGD
Official Full Name
galactose-3-O-sulfotransferase 1provided by RGD
Primary source
RGD:1583379
See related
EnsemblRapid:ENSRNOG00000042041 AllianceGenome:RGD:1583379
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable galactosylceramide sulfotransferase activity. Predicted to be involved in galactosylceramide biosynthetic process; glycerolipid metabolic process; and myelination. Predicted to act upstream of or within spermatogenesis. Predicted to be located in membrane. Orthologous to human GAL3ST1 (galactose-3-O-sulfotransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 23.9), Brain (RPKM 19.5) and 3 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Gal3st1 in Genome Data Viewer
Location:
14q21
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (83094265..83109992)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (78868049..78886402)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (84231473..84247371)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene transcobalamin 2 Neighboring gene pescadillo ribosomal biogenesis factor 1 Neighboring gene SEC14-like lipid binding 4 Neighboring gene uncharacterized LOC103693135 Neighboring gene uncharacterized LOC120096646

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. cDNA cloning, genomic cloning, and tissue-specific regulation of mouse cerebroside sulfotransferase. Hirahara Y, et al. Eur J Biochem, 2000 Apr. PMID 10727929
  2. Paranodal junction formation and spermatogenesis require sulfoglycolipids. Honke K, et al. Proc Natl Acad Sci U S A, 2002 Apr 2. PMID 11917099, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables galactosylceramide sulfotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables galactosylceramide sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in galactosylceramide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within galactosylceramide biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in galactosylceramide metabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in glycerolipid metabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in myelination IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within myelination ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within spermatogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in sphingolipid metabolic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
galactosylceramide sulfotransferase
NP_001102917.1
XP_006251444.1
XP_006251445.1
XP_063129696.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109447.1 → NP_001102917.1  galactosylceramide sulfotransferase

    See identical proteins and their annotated locations for NP_001102917.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473963
    UniProtKB/TrEMBL
    A6IKE0, D3ZCT9
    Related
    ENSRNOP00000062589.2, ENSRNOT00000066362.4
    Conserved Domains (1) summary
    cl22970
    Location:31 → 440
    Sulfotransfer_2; Sulfotransferase family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    83094265..83109992
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006251382.5 → XP_006251444.1  galactosylceramide sulfotransferase isoform X2

    See identical proteins and their annotated locations for XP_006251444.1

    UniProtKB/TrEMBL
    Q5PQK7
    Conserved Domains (1) summary
    cl22970
    Location:4 → 408
    Sulfotransfer_2; Sulfotransferase family

  2. XM_063273626.1 → XP_063129696.1  galactosylceramide sulfotransferase isoform X1

  3. XM_006251383.5 → XP_006251445.1  galactosylceramide sulfotransferase isoform X2

    See identical proteins and their annotated locations for XP_006251445.1

    UniProtKB/TrEMBL
    Q5PQK7
    Conserved Domains (1) summary
    cl22970
    Location:4 → 408
    Sulfotransfer_2; Sulfotransferase family
Nucleotide Protein Strain
Heading Accession and Version

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