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mllt1b MLLT1 super elongation complex subunit b [ Danio rerio (zebrafish) ]

Gene ID: 678639, updated on 2-Nov-2024

Summary

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Official Symbol
mllt1bprovided by ZNC
Official Full Name
MLLT1 super elongation complex subunit bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060421-7142
See related
Ensembl:ENSDARG00000031709 AllianceGenome:ZFIN:ZDB-GENE-060421-7142
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fj79f01; zgc:136639
Summary
Predicted to enable chromatin binding activity and lysine-acetylated histone binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Is expressed in prechordal plate. Orthologous to human MLLT1 (MLLT1 super elongation complex subunit). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See mllt1b in Genome Data Viewer
Location:
chromosome: 2
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (22970124..22993624, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (23314469..23338017, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene myosin VIIBb Neighboring gene uncharacterized LOC103910043 Neighboring gene Sin3A-associated protein b Neighboring gene zinc finger protein 414 Neighboring gene MAPK interacting serine/threonine kinase 2a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis. Farrell JA, et al. Science, 2018 Jun 1. PMID 29700225, Free PMC Article
  2. Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Zhang Y, et al. Cell Rep, 2017 Jan 10. PMID 28076796, Free PMC Article
  3. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC136639

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lysine-acetylated histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription elongation factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
MLLT1 super elongation complex subunit b
Names
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 b
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040384.1 → NP_001035474.1  MLLT1 super elongation complex subunit b

    See identical proteins and their annotated locations for NP_001035474.1

    Status: PROVISIONAL

    Source sequence(s)
    BC115206
    UniProtKB/TrEMBL
    Q1RM01
    Related
    ENSDARP00000090508.3, ENSDART00000099735.5
    Conserved Domains (1) summary
    pfam03366
    Location:29 → 109
    YEATS; YEATS family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    22970124..22993624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068224918.1 → XP_068081019.1  MLLT1 super elongation complex subunit b isoform X5

  2. XM_009298518.4 → XP_009296793.1  MLLT1 super elongation complex subunit b isoform X4

    UniProtKB/TrEMBL
    A0A8M3B092
    Conserved Domains (1) summary
    pfam03366
    Location:29 → 109
    YEATS; YEATS family

  3. XM_009298517.4 → XP_009296792.1  MLLT1 super elongation complex subunit b isoform X2

    UniProtKB/TrEMBL
    A0A8M3AQ75
    Conserved Domains (1) summary
    pfam03366
    Location:29 → 109
    YEATS; YEATS family

  4. XM_005171213.5 → XP_005171270.1  MLLT1 super elongation complex subunit b isoform X3

    UniProtKB/TrEMBL
    A0A8M2BIX7
    Conserved Domains (1) summary
    pfam03366
    Location:29 → 109
    YEATS; YEATS family

  5. XM_005171212.5 → XP_005171269.1  MLLT1 super elongation complex subunit b isoform X1

    UniProtKB/TrEMBL
    A0A8M2BIJ1
    Conserved Domains (1) summary
    pfam03366
    Location:29 → 109
    YEATS; YEATS family

  6. XM_009298519.4 → XP_009296794.1  MLLT1 super elongation complex subunit b isoform X6

    UniProtKB/TrEMBL
    A0A8M3AX88
    Conserved Domains (1) summary
    pfam03366
    Location:29 → 109
    YEATS; YEATS family
Nucleotide Protein Strain
Heading Accession and Version

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