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Ceacam12 CEA cell adhesion molecule 12 [ Mus musculus (house mouse) ]

Gene ID: 67315, updated on 18-Sep-2024

Summary

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Official Symbol
Ceacam12provided by MGI
Official Full Name
CEA cell adhesion molecule 12provided by MGI
Primary source
MGI:MGI:1914565
See related
Ensembl:ENSMUSG00000030366 AllianceGenome:MGI:1914565
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ceacam12C1; Ceacam12C3; Ceacam12-C1; Ceacam12-C3; 1600031J20Rik
Summary
Predicted to be involved in phagocytosis. Orthologous to human CEACAM21 (CEA cell adhesion molecule 21) and CEACAM4 (CEA cell adhesion molecule 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward placenta adult (RPKM 52.9) See more
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Genomic context

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See Ceacam12 in Genome Data Viewer
Location:
7 A2; 7 9.15 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (17799854..17811911)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (18065929..18077986)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CEA cell adhesion molecule 13 Neighboring gene eukaryotic translation initiation factor pseudogene Neighboring gene STARR-seq mESC enhancer starr_18163 Neighboring gene IGF-like family member 3 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. HEMOGLOBINS IN MICE. SEGREGATION OF GENETIC FACTORS AFFECTING ELECTROPHORETIC MOBILITY AND SOLUBILITY. WOLFE HG, et al. J Hered, 1963 May-Jun. PMID 14051862
  2. Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. Zebhauser R, et al. Genomics, 2005 Nov. PMID 16139472
  3. Peg3 mutational effects on reproduction and placenta-specific gene families. Kim J, et al. PLoS One, 2013. PMID 24391757, Free PMC Article
  4. Genomic evolution of the placenta using co-option and duplication and divergence. Knox K, et al. Genome Res, 2008 May. PMID 18340042, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Clone Names

  • MGC117634

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in T cell activation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
carcinoembryonic antigen-related cell adhesion molecule 12
Names
CEA-related cell adhesion molecule 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162523.1 → NP_001155995.1  carcinoembryonic antigen-related cell adhesion molecule 12 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001155995.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC133088, AK005400, AK131656
    Consensus CDS
    CCDS52047.1
    UniProtKB/TrEMBL
    Q3V2Q3, Q9DAZ3
    Related
    ENSMUSP00000104127.3, ENSMUST00000108487.9
    Conserved Domains (1) summary
    cd05774
    Location:36 → 140
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

  2. NM_001162524.2 → NP_001155996.1  carcinoembryonic antigen-related cell adhesion molecule 12 isoform 3 precursor

    See identical proteins and their annotated locations for NP_001155996.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (3) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    BC099443, BY705606
    Consensus CDS
    CCDS52048.1
    UniProtKB/TrEMBL
    Q9DAS5, Q9DAZ3
    Related
    ENSMUSP00000104123.2, ENSMUST00000108483.2
    Conserved Domains (1) summary
    cd05774
    Location:36 → 140
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

  3. NM_026087.3 → NP_080363.2  carcinoembryonic antigen-related cell adhesion molecule 12 isoform 1 precursor

    See identical proteins and their annotated locations for NP_080363.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shortest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC133088, AK005400, AK145926
    Consensus CDS
    CCDS20867.1
    UniProtKB/TrEMBL
    Q3UKP4, Q9DAZ3
    Related
    ENSMUSP00000032520.3, ENSMUST00000032520.9
    Conserved Domains (1) summary
    cd05774
    Location:36 → 140
    Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    17799854..17811911
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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