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GCK glucokinase [ Canis lupus familiaris (dog) ]

Gene ID: 606490, updated on 17-Aug-2024

Summary

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Official Symbol
GCKprovided by VGNC
Official Full Name
glucokinaseprovided by VGNC
Primary source
VGNC:VGNC:111508
See related
Ensembl:ENSCAFG00845013118
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See GCK in Genome Data Viewer
Location:
chromosome: 16
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 16 NC_051820.1 (14737904..14781009)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 16 NC_006598.4 (2080944..2123987, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 16 NC_049237.1 (14349631..14392705)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 16 NC_049757.1 (14369169..14412232)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) Unplaced Scaffold NW_023332296.1 (758331..801402)

Chromosome 16 - NC_051820.1Genomic Context describing neighboring genes Neighboring gene calcium/calmodulin dependent protein kinase II beta Neighboring gene uncharacterized LOC119869528 Neighboring gene YKT6 v-SNARE homolog Neighboring gene uncharacterized LOC119869537 Neighboring gene myosin light chain 7 Neighboring gene DNA polymerase delta 2, accessory subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables D-glucose binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glucokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mannokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glucose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of insulin secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hexokinase-4
Names
glucokinase (hexokinase 4)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051820.1 Reference ROS_Cfam_1.0

    Range
    14737904..14781009
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038689301.1 → XP_038545229.1  hexokinase-4 isoform X2

    Conserved Domains (2) summary
    pfam00349
    Location:15 → 215
    Hexokinase_1
    pfam03727
    Location:221 → 337
    Hexokinase_2

  2. XM_038689300.1 → XP_038545228.1  hexokinase-4 isoform X2

    Related
    ENSCAFP00845018333.1, ENSCAFT00845023360.1
    Conserved Domains (2) summary
    pfam00349
    Location:15 → 215
    Hexokinase_1
    pfam03727
    Location:221 → 337
    Hexokinase_2

  3. XM_038689302.1 → XP_038545230.1  hexokinase-4 isoform X3

    Conserved Domains (2) summary
    pfam00349
    Location:3 → 191
    Hexokinase_1
    pfam03727
    Location:197 → 313
    Hexokinase_2

  4. XM_038689299.1 → XP_038545227.1  hexokinase-4 isoform X1

    Related
    ENSCAFP00845018350.1, ENSCAFT00845023382.1
    Conserved Domains (2) summary
    pfam00349
    Location:18 → 216
    Hexokinase_1
    pfam03727
    Location:222 → 338
    Hexokinase_2

  5. XM_038689303.1 → XP_038545231.1  hexokinase-4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0KSU5, A0A8I3NNP9
    Related
    ENSCAFP00845018396.1, ENSCAFT00845023439.1
    Conserved Domains (2) summary
    pfam00349
    Location:18 → 216
    Hexokinase_1
    pfam03727
    Location:222 → 456
    Hexokinase_2

  6. XM_038689304.1 → XP_038545232.1  hexokinase-4 isoform X5

    Conserved Domains (1) summary
    pfam03727
    Location:14 → 158
    Hexokinase_2

  7. XM_038689305.1 → XP_038545233.1  hexokinase-4 isoform X6

    Conserved Domains (1) summary
    pfam03727
    Location:1 → 75
    Hexokinase_2

  8. XM_038689306.1 → XP_038545234.1  hexokinase-4 isoform X6

    Conserved Domains (1) summary
    pfam03727
    Location:1 → 75
    Hexokinase_2

Alternate UMICH_Zoey_3.1

Genomic

  1. NW_023332296.1 Alternate UMICH_Zoey_3.1

    Range
    758331..801402
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038525235.1 → XP_038381163.1  hexokinase-4 isoform X2

    Conserved Domains (2) summary
    pfam00349
    Location:15 → 215
    Hexokinase_1
    pfam03727
    Location:221 → 337
    Hexokinase_2

  2. XM_038525234.1 → XP_038381162.1  hexokinase-4 isoform X2

    Conserved Domains (2) summary
    pfam00349
    Location:15 → 215
    Hexokinase_1
    pfam03727
    Location:221 → 337
    Hexokinase_2

  3. XM_038525236.1 → XP_038381164.1  hexokinase-4 isoform X3

    Conserved Domains (2) summary
    pfam00349
    Location:3 → 191
    Hexokinase_1
    pfam03727
    Location:197 → 313
    Hexokinase_2

  4. XM_038525233.1 → XP_038381161.1  hexokinase-4 isoform X1

    Conserved Domains (2) summary
    pfam00349
    Location:18 → 216
    Hexokinase_1
    pfam03727
    Location:222 → 338
    Hexokinase_2

  5. XM_038525237.1 → XP_038381165.1  hexokinase-4 isoform X4

    Conserved Domains (2) summary
    pfam00349
    Location:18 → 216
    Hexokinase_1
    pfam03727
    Location:222 → 456
    Hexokinase_2

  6. XM_038525238.1 → XP_038381166.1  hexokinase-4 isoform X5

    Conserved Domains (1) summary
    pfam03727
    Location:14 → 158
    Hexokinase_2

  7. XM_038525239.1 → XP_038381167.1  hexokinase-4 isoform X6

    Conserved Domains (1) summary
    pfam03727
    Location:1 → 75
    Hexokinase_2

  8. XM_038525240.1 → XP_038381168.1  hexokinase-4 isoform X6

    Conserved Domains (1) summary
    pfam03727
    Location:1 → 75
    Hexokinase_2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049757.1 Alternate UNSW_CanFamBas_1.0

    Range
    14369169..14412232
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038623564.1 → XP_038479492.1  hexokinase-4 isoform X2

    Conserved Domains (2) summary
    pfam00349
    Location:15 → 215
    Hexokinase_1
    pfam03727
    Location:221 → 337
    Hexokinase_2

  2. XM_038623563.1 → XP_038479491.1  hexokinase-4 isoform X2

    Conserved Domains (2) summary
    pfam00349
    Location:15 → 215
    Hexokinase_1
    pfam03727
    Location:221 → 337
    Hexokinase_2

  3. XM_038623565.1 → XP_038479493.1  hexokinase-4 isoform X3

    Conserved Domains (2) summary
    pfam00349
    Location:3 → 191
    Hexokinase_1
    pfam03727
    Location:197 → 313
    Hexokinase_2

  4. XM_038623562.1 → XP_038479490.1  hexokinase-4 isoform X1

    Conserved Domains (2) summary
    pfam00349
    Location:18 → 216
    Hexokinase_1
    pfam03727
    Location:222 → 338
    Hexokinase_2

  5. XM_038623566.1 → XP_038479494.1  hexokinase-4 isoform X4

    Conserved Domains (2) summary
    pfam00349
    Location:18 → 216
    Hexokinase_1
    pfam03727
    Location:222 → 456
    Hexokinase_2

  6. XM_038623567.1 → XP_038479495.1  hexokinase-4 isoform X5

    Conserved Domains (1) summary
    pfam03727
    Location:14 → 158
    Hexokinase_2

  7. XM_038623568.1 → XP_038479496.1  hexokinase-4 isoform X6

    Conserved Domains (1) summary
    pfam03727
    Location:1 → 75
    Hexokinase_2

  8. XM_038623569.1 → XP_038479497.1  hexokinase-4 isoform X6

    Conserved Domains (1) summary
    pfam03727
    Location:1 → 75
    Hexokinase_2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049237.1 Alternate UU_Cfam_GSD_1.0

    Range
    14349631..14392705
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038559568.1 → XP_038415496.1  hexokinase-4 isoform X2

    Conserved Domains (2) summary
    pfam00349
    Location:15 → 215
    Hexokinase_1
    pfam03727
    Location:221 → 337
    Hexokinase_2

  2. XM_038559567.1 → XP_038415495.1  hexokinase-4 isoform X2

    Conserved Domains (2) summary
    pfam00349
    Location:15 → 215
    Hexokinase_1
    pfam03727
    Location:221 → 337
    Hexokinase_2

  3. XM_038559569.1 → XP_038415497.1  hexokinase-4 isoform X3

    Conserved Domains (2) summary
    pfam00349
    Location:3 → 191
    Hexokinase_1
    pfam03727
    Location:197 → 313
    Hexokinase_2

  4. XM_038559566.1 → XP_038415494.1  hexokinase-4 isoform X1

    Conserved Domains (2) summary
    pfam00349
    Location:18 → 216
    Hexokinase_1
    pfam03727
    Location:222 → 338
    Hexokinase_2

  5. XM_038559570.1 → XP_038415498.1  hexokinase-4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0KSU5, A0A8I3NNP9
    Conserved Domains (2) summary
    pfam00349
    Location:18 → 216
    Hexokinase_1
    pfam03727
    Location:222 → 456
    Hexokinase_2

  6. XM_038559571.1 → XP_038415499.1  hexokinase-4 isoform X5

    Conserved Domains (1) summary
    pfam03727
    Location:14 → 158
    Hexokinase_2

  7. XM_038559572.1 → XP_038415500.1  hexokinase-4 isoform X6

    Conserved Domains (1) summary
    pfam03727
    Location:1 → 75
    Hexokinase_2

  8. XM_038559573.1 → XP_038415501.1  hexokinase-4 isoform X6

    Conserved Domains (1) summary
    pfam03727
    Location:1 → 75
    Hexokinase_2

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006598.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    2080944..2123987 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038452450.1 → XP_038308378.1  hexokinase-4 isoform X2

    Conserved Domains (2) summary
    pfam00349
    Location:15 → 215
    Hexokinase_1
    pfam03727
    Location:221 → 337
    Hexokinase_2

  2. XM_038452452.1 → XP_038308380.1  hexokinase-4 isoform X3

    Conserved Domains (2) summary
    pfam00349
    Location:3 → 191
    Hexokinase_1
    pfam03727
    Location:197 → 313
    Hexokinase_2

  3. XM_038452449.1 → XP_038308377.1  hexokinase-4 isoform X1

    Conserved Domains (2) summary
    pfam00349
    Location:18 → 216
    Hexokinase_1
    pfam03727
    Location:222 → 338
    Hexokinase_2

  4. XM_038452453.1 → XP_038308381.1  hexokinase-4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0KSU5, A0A8I3NNP9
    Conserved Domains (2) summary
    pfam00349
    Location:18 → 216
    Hexokinase_1
    pfam03727
    Location:222 → 456
    Hexokinase_2

  5. XM_038452454.1 → XP_038308382.1  hexokinase-4 isoform X5

    Conserved Domains (1) summary
    pfam03727
    Location:14 → 158
    Hexokinase_2

  6. XM_038452455.1 → XP_038308383.1  hexokinase-4 isoform X6

    Conserved Domains (1) summary
    pfam03727
    Location:1 → 75
    Hexokinase_2

  7. XM_038452456.1 → XP_038308384.1  hexokinase-4 isoform X6

    Conserved Domains (1) summary
    pfam03727
    Location:1 → 75
    Hexokinase_2
Nucleotide Protein
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