ccnl2 cyclin L2 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: ccnl2provided by Xenbase
Official Full Name: cyclin L2provided by Xenbase
Primary source: Xenbase:XB-GENE-956522
See related: Ensembl:ENSXETG00000017379 AllianceGenome:Xenbase:XB-GENE-956522
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Orthologous to human CCNL2 (cyclin L2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	7	NC_030683.2 (92964372..92974899)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	7	NC_030683.1 (70090390..70100186, complement)

Chromosome 7 - NC_030683.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables cyclin-dependent protein serine/threonine kinase regulator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nuclear speck	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cyclin-L2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001030452.1 → NP_001025623.1 cyclin-L2

See identical proteins and their annotated locations for NP_001025623.1

Status: PROVISIONAL

Source sequence(s)

BC091090

UniProtKB/Swiss-Prot

Q5BKF8

UniProtKB/TrEMBL

G1K3E7

Related

ENSXETP00000024290.4, ENSXETT00000024290.5

Conserved Domains (2) summary

smart00385
Location:178 → 260

CYCLIN; domain present in cyclins, TFIIB and Retinoblastoma

cd00043
Location:55 → 128

CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

92964372..92974899

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_012966672.2 → XP_012822126.1 cyclin-L2 isoform X1

UniProtKB/TrEMBL

A0A8J0STZ8, G1K3E7

Related

ENSXETP00000068955.2, ENSXETT00000082091.2

Conserved Domains (2) summary

smart00385
Location:183 → 265

CYCLIN; domain present in cyclins, TFIIB and Retinoblastoma

cd00043
Location:60 → 133

CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...