U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PTK7 protein tyrosine kinase 7 (inactive) [ Homo sapiens (human) ]

Gene ID: 5754, updated on 14-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
PTK7provided by HGNC
Official Full Name
protein tyrosine kinase 7 (inactive)provided by HGNC
Primary source
HGNC:HGNC:9618
See related
Ensembl:ENSG00000112655 MIM:601890; AllianceGenome:HGNC:9618
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CCK4; CCK-4
Summary
This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Expression
Broad expression in endometrium (RPKM 43.5), ovary (RPKM 31.2) and 19 other tissues See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PTK7 in Genome Data Viewer
Location:
6p21.1
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (43076314..43161715)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (42905060..42990493)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (43044052..43129453)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24587 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:43027385-43028336 Neighboring gene Sharpr-MPRA regulatory region 10128 Neighboring gene mitochondrial ribosomal protein L2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:43038920-43039420 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:43043187-43043710 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17218 Neighboring gene kinesin light chain 4 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:43049243-43049446 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:43050481-43051047 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:43051048-43051613 Neighboring gene KLC4 antisense RNA 1 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:43057365-43057958 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr6:43057959-43058553 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:43058554-43059147 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24589 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24590 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24591 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:43086921-43087840 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:43087841-43088760 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:43099803-43100304 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:43100305-43100804 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24592 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:43138211-43138940 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17219 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:43139967-43140935 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24594 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:43145601-43146102 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:43146103-43146602 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24595 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17220 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17221 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr6:43154118-43155317 Neighboring gene serum response factor Neighboring gene cullin 9 Neighboring gene MPRA-validated peak5812 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:43190560-43191097 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24596

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. PTK7 is a molecular marker for metastasis, TNM stage, and prognosis in oral tongue squamous cell carcinoma. Dong Y, et al. Pol J Pathol, 2017. PMID 28547980
  2. PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis. Wang H, et al. Int J Clin Exp Pathol, 2014. PMID 25550828, Free PMC Article
  3. Protein tyrosine kinase 7: a hepatocellular carcinoma-related gene detected by triple-combination array. Hishida M, et al. J Surg Res, 2015 May 15. PMID 25796105
  4. Overexpression of the Promigratory and Prometastatic PTK7 Receptor Is Associated with an Adverse Clinical Outcome in Colorectal Cancer. Lhoumeau AC, et al. PLoS One, 2015. PMID 25962058, Free PMC Article
  5. Role of the planar cell polarity gene Protein tyrosine kinase 7 in neural tube defects in humans. Wang M, et al. Birth Defects Res A Clin Mol Teratol, 2015 Dec. PMID 26368655

See all (126) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. FOXP4-mediated induction of PTK7 activates the Wnt/beta-catenin pathway and promotes ovarian cancer development.
    Title: FOXP4-mediated induction of PTK7 activates the Wnt/β-catenin pathway and promotes ovarian cancer development.
  2. Elucidating the Functional Mechanism of PTK7 in Cancer Development through Spatial Assembly Analysis Using Super Resolution Imaging.
    Title: Elucidating the Functional Mechanism of PTK7 in Cancer Development through Spatial Assembly Analysis Using Super Resolution Imaging.
  3. Knockdown of PTK7 Reduces the Oncogenic Potential of Breast Cancer Cells by Impeding Receptor Tyrosine Kinase Signaling.
    Title: Knockdown of PTK7 Reduces the Oncogenic Potential of Breast Cancer Cells by Impeding Receptor Tyrosine Kinase Signaling.
  4. Proteomic and Phosphoproteomic Analyses Reveal the Oncogenic Role of PTK7-NDRG1 Axis in Non-small-cell Lung Cancer Cell Resistance to AZD9291.
    Title: Proteomic and Phosphoproteomic Analyses Reveal the Oncogenic Role of PTK7-NDRG1 Axis in Non-small-cell Lung Cancer Cell Resistance to AZD9291.
  5. Diverse ancestry whole-genome sequencing association study identifies TBX5 and PTK7 as susceptibility genes for posterior urethral valves.
    Title: Diverse ancestry whole-genome sequencing association study identifies TBX5 and PTK7 as susceptibility genes for posterior urethral valves.
  6. High expression of protein tyrosine kinase 7 in oral squamous cell carcinoma: Clinicopathological correlation and prognosis relevance.
    Title: High expression of protein tyrosine kinase 7 in oral squamous cell carcinoma: Clinicopathological correlation and prognosis relevance.
  7. PTK7, a Catalytically Inactive Receptor Tyrosine Kinase, Increases Oncogenic Phenotypes in Xenograft Tumors of Esophageal Squamous Cell Carcinoma KYSE-30 Cells.
    Title: PTK7, a Catalytically Inactive Receptor Tyrosine Kinase, Increases Oncogenic Phenotypes in Xenograft Tumors of Esophageal Squamous Cell Carcinoma KYSE-30 Cells.
  8. Whole-Exome Sequencing Identifies a Novel Germline Variant in PTK7 Gene in Familial Colorectal Cancer.
    Title: Whole-Exome Sequencing Identifies a Novel Germline Variant in PTK7 Gene in Familial Colorectal Cancer.
  9. The Mutational Landscape of PTK7 in Congenital Scoliosis and Adolescent Idiopathic Scoliosis.
    Title: The Mutational Landscape of PTK7 in Congenital Scoliosis and Adolescent Idiopathic Scoliosis.
  10. LncRNA-MALAT1 regulates proliferation and apoptosis of acute lymphoblastic leukemia cells via miR-205-PTK7 pathway.
    Title: LncRNA-MALAT1 regulates proliferation and apoptosis of acute lymphoblastic leukemia cells via miR-205-PTK7 pathway.
Submit: New GeneRIF Correction See all GeneRIFs (57)

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables axon guidance receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables coreceptor activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in axis elongation IEA
Inferred from Electronic Annotation
more info
  
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
  
involved_in cell migration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to retinoic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cochlea morphogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in convergent extension IEA
Inferred from Electronic Annotation
more info
  
involved_in coronary vasculature development IEA
Inferred from Electronic Annotation
more info
  
involved_in establishment of epithelial cell apical/basal polarity IEA
Inferred from Electronic Annotation
more info
  
involved_in establishment of planar polarity IEA
Inferred from Electronic Annotation
more info
  
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in kidney development IEA
Inferred from Electronic Annotation
more info
  
involved_in lung-associated mesenchyme development IEA
Inferred from Electronic Annotation
more info
  
involved_in neural tube closure IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of canonical Wnt signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of neuron projection development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signal transduction TAS
Traceable Author Statement
more info
 PubMed 
involved_in synapse organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ventricular septum development IEA
Inferred from Electronic Annotation
more info
  
involved_in wound healing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cell-cell junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cell-cell junction IDA
Inferred from Direct Assay
more info
 PubMed 
located_in focal adhesion HDA PubMed 
is_active_in neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
inactive tyrosine-protein kinase 7
Names
PTK7 protein tyrosine kinase 7
colon carcinoma kinase 4
pseudo tyrosine kinase receptor 7
tyrosine-protein kinase-like 7
NP_001257327.1
NP_002812.2
NP_690619.1
NP_690620.1
NP_690621.1
XP_011513067.1
XP_011513068.1
XP_047275113.1
XP_054212039.1
XP_054212040.1
XP_054212041.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001270398.2 → NP_001257327.1  inactive tyrosine-protein kinase 7 isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant PTK7-1. The encoded isoform (e) is longer and has a distinct N-terminus, compared to isoform a.
    Source sequence(s)
    AI140260, AK291016, AK296953, BQ881986, CN266652
    Consensus CDS
    CCDS59021.1
    UniProtKB/Swiss-Prot
    Q13308
    Related
    ENSP00000418754.1, ENST00000481273.5
    Conserved Domains (9) summary
    cd05046
    Location:798 → 1071
    PTK_CCK4; Pseudokinase domain of the Protein Tyrosine Kinase, Colon Carcinoma Kinase 4
    cd00096
    Location:250 → 310
    Ig; Immunoglobulin domain
    cd05760
    Location:154 → 230
    Ig2_PTK7; Second immunoglobulin (Ig)-like domain of protein tyrosine kinase (PTK) 7, also known as CCK4
    smart00408
    Location:613 → 677
    IGc2; Immunoglobulin C-2 Type
    smart00221
    Location:809 → 1069
    STYKc; Protein kinase; unclassified specificity
    smart00409
    Location:348 → 416
    IG; Immunoglobulin
    smart00410
    Location:606 → 689
    IG_like; Immunoglobulin like
    pfam07679
    Location:420 → 506
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:422 → 506
    Ig; Immunoglobulin domain

  2. NM_002821.5 → NP_002812.2  inactive tyrosine-protein kinase 7 isoform a precursor

    See identical proteins and their annotated locations for NP_002812.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (PTK7-1) represents the longest transcript and encodes isoform a.
    Source sequence(s)
    AF531868, AI140260, AK291016, CA389442
    Consensus CDS
    CCDS4884.1
    UniProtKB/Swiss-Prot
    A8K974, B7Z477, E9PFZ5, Q13308, Q13417, Q5T650, Q6IQ54, Q8NFA5, Q8NFA6, Q8NFA7, Q8NFA8
    Related
    ENSP00000230419.4, ENST00000230419.9
    Conserved Domains (8) summary
    cd05046
    Location:790 → 1063
    PTK_CCK4; Pseudokinase domain of the Protein Tyrosine Kinase, Colon Carcinoma Kinase 4
    cd00096
    Location:242 → 302
    Ig; Immunoglobulin domain
    cd05760
    Location:146 → 222
    Ig2_PTK7; Second immunoglobulin (Ig)-like domain of protein tyrosine kinase (PTK) 7, also known as CCK4
    smart00408
    Location:605 → 669
    IGc2; Immunoglobulin C-2 Type
    smart00221
    Location:801 → 1061
    STYKc; Protein kinase; unclassified specificity
    smart00410
    Location:598 → 681
    IG_like; Immunoglobulin like
    pfam07679
    Location:412 → 498
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:414 → 498
    Ig; Immunoglobulin domain

  3. NM_152880.4 → NP_690619.1  inactive tyrosine-protein kinase 7 isoform b precursor

    See identical proteins and their annotated locations for NP_690619.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (PTK7-2) lacks an exon in the coding region, but maintains the reading frame, compared to variant PTK7-1. The encoded isoform (b) is shorter than isoform a.
    Source sequence(s)
    AF531869, AI140260, AK291016, CA389442
    Consensus CDS
    CCDS4885.1
    UniProtKB/Swiss-Prot
    Q13308
    Related
    ENSP00000325992.4, ENST00000345201.6
    Conserved Domains (9) summary
    cd05046
    Location:750 → 1023
    PTK_CCK4; Pseudokinase domain of the Protein Tyrosine Kinase, Colon Carcinoma Kinase 4
    cd00096
    Location:242 → 302
    Ig; Immunoglobulin domain
    cd05760
    Location:146 → 222
    Ig2_PTK7; Second immunoglobulin (Ig)-like domain of protein tyrosine kinase (PTK) 7, also known as CCK4
    smart00408
    Location:565 → 629
    IGc2; Immunoglobulin C-2 Type
    smart00221
    Location:761 → 1021
    STYKc; Protein kinase; unclassified specificity
    smart00409
    Location:231 → 301
    IG; Immunoglobulin
    smart00410
    Location:558 → 641
    IG_like; Immunoglobulin like
    pfam07679
    Location:412 → 498
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:414 → 498
    Ig; Immunoglobulin domain

  4. NM_152881.4 → NP_690620.1  inactive tyrosine-protein kinase 7 isoform c precursor

    See identical proteins and their annotated locations for NP_690620.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (PTK7-3) lacks three consecutive exons in the coding region, but maintains the reading frame, compared to variant PTK7-1. The encoded isoform (c) is shorter than isoform a.
    Source sequence(s)
    AF531870, AI140260, AK291016, CA389442
    Consensus CDS
    CCDS4886.1
    UniProtKB/Swiss-Prot
    Q13308
    Related
    ENSP00000325462.4, ENST00000349241.6
    Conserved Domains (6) summary
    cd05046
    Location:660 → 933
    PTK_CCK4; Pseudokinase domain of the Protein Tyrosine Kinase, Colon Carcinoma Kinase 4
    cd00096
    Location:242 → 302
    Ig; Immunoglobulin domain
    cd05760
    Location:146 → 222
    Ig2_PTK7; Second immunoglobulin (Ig)-like domain of protein tyrosine kinase (PTK) 7, also known as CCK4
    smart00408
    Location:475 → 539
    IGc2; Immunoglobulin C-2 Type
    smart00221
    Location:671 → 931
    STYKc; Protein kinase; unclassified specificity
    smart00410
    Location:468 → 551
    IG_like; Immunoglobulin like

  5. NM_152882.4 → NP_690621.1  inactive tyrosine-protein kinase 7 isoform d precursor

    See identical proteins and their annotated locations for NP_690621.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (PTK7-4) uses an alternate splice site and lacks an exon in the coding region, but maintains the reading frame, compared to variant PTK7-1. The encoded isoform (d) is shorter than isoform a.
    Source sequence(s)
    AF531871, AI140260, AK291016, CA389442
    Consensus CDS
    CCDS4887.1
    UniProtKB/Swiss-Prot
    Q13308
    Related
    ENSP00000326029.3, ENST00000352931.6
    Conserved Domains (9) summary
    cd05046
    Location:734 → 1007
    PTK_CCK4; Pseudokinase domain of the Protein Tyrosine Kinase, Colon Carcinoma Kinase 4
    cd00096
    Location:242 → 302
    Ig; Immunoglobulin domain
    cd05760
    Location:146 → 222
    Ig2_PTK7; Second immunoglobulin (Ig)-like domain of protein tyrosine kinase (PTK) 7, also known as CCK4
    smart00408
    Location:520 → 574
    IGc2; Immunoglobulin C-2 Type
    smart00221
    Location:745 → 1005
    STYKc; Protein kinase; unclassified specificity
    smart00409
    Location:231 → 301
    IG; Immunoglobulin
    smart00410
    Location:38 → 112
    IG_like; Immunoglobulin like
    pfam07679
    Location:412 → 498
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:414 → 498
    Ig; Immunoglobulin domain

RNA

  1. NR_072997.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) lacks an internal exon, compared to variant PTK7-1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant PTK7-1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    BC014626, CA389442, DA048438
    Related
    ENST00000470019.5

  2. NR_072998.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (PTK7-5) lacks an internal exon, compared to variant PTK7-1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant PTK7-1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AF531872, AI140260, AK291016, CA389442
    Related
    ENST00000230418.8

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    43076314..43161715
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011514765.3 → XP_011513067.1  inactive tyrosine-protein kinase 7 isoform X1

    Conserved Domains (9) summary
    cd05046
    Location:758 → 1031
    PTK_CCK4; Pseudokinase domain of the Protein Tyrosine Kinase, Colon Carcinoma Kinase 4
    cd00096
    Location:250 → 310
    Ig; Immunoglobulin domain
    cd05760
    Location:154 → 230
    Ig2_PTK7; Second immunoglobulin (Ig)-like domain of protein tyrosine kinase (PTK) 7, also known as CCK4
    smart00408
    Location:573 → 637
    IGc2; Immunoglobulin C-2 Type
    smart00221
    Location:769 → 1029
    STYKc; Protein kinase; unclassified specificity
    smart00409
    Location:239 → 309
    IG; Immunoglobulin
    smart00410
    Location:566 → 649
    IG_like; Immunoglobulin like
    pfam07679
    Location:420 → 506
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:422 → 506
    Ig; Immunoglobulin domain

  2. XM_011514766.3 → XP_011513068.1  inactive tyrosine-protein kinase 7 isoform X2

    Conserved Domains (6) summary
    cd05046
    Location:668 → 941
    PTK_CCK4; Pseudokinase domain of the Protein Tyrosine Kinase, Colon Carcinoma Kinase 4
    cd00096
    Location:250 → 310
    Ig; Immunoglobulin domain
    cd05760
    Location:154 → 230
    Ig2_PTK7; Second immunoglobulin (Ig)-like domain of protein tyrosine kinase (PTK) 7, also known as CCK4
    smart00408
    Location:483 → 547
    IGc2; Immunoglobulin C-2 Type
    smart00221
    Location:679 → 939
    STYKc; Protein kinase; unclassified specificity
    smart00410
    Location:476 → 559
    IG_like; Immunoglobulin like

  3. XM_047419157.1 → XP_047275113.1  inactive tyrosine-protein kinase 7 isoform X3

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    42905060..42990493
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054356064.1 → XP_054212039.1  inactive tyrosine-protein kinase 7 isoform X1

  2. XM_054356065.1 → XP_054212040.1  inactive tyrosine-protein kinase 7 isoform X2

  3. XM_054356066.1 → XP_054212041.1  inactive tyrosine-protein kinase 7 isoform X3

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_152883.1: Suppressed sequence

    Description
    NM_152883.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q13308.2 GenPept UniProtKB/Swiss-Prot:Q13308

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools