dse dermatan sulfate epimerase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dseprovided by ZNC
Official Full Name: dermatan sulfate epimeraseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041001-202
See related: Ensembl:ENSDARG00000017988 AllianceGenome:ZFIN:ZDB-GENE-041001-202
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:dkey-121j17.2
Summary: Predicted to enable chondroitin-glucuronate 5-epimerase activity. Predicted to be involved in chondroitin sulfate metabolic process and dermatan sulfate metabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in head; immature eye; pectoral fin; and somite. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome musculocontractural type 2. Orthologous to human DSE (dermatan sulfate epimerase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (535481..556740)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (545569..566807)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables chondroitin-glucuronate 5-epimerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables chondroitin-glucuronate 5-epimerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in chondroitin sulfate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in dermatan sulfate metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dermatan-sulfate epimerase

NP_001025396.1

EC 5.1.3.19

XP_005164481.1

EC 5.1.3.19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.