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foxf1 forkhead box F1 [ Danio rerio (zebrafish) ]

Gene ID: 566407, updated on 2-Nov-2024

Summary

Official Symbol
foxf1provided by ZNC
Official Full Name
forkhead box F1provided by ZNC
Primary source
ZFIN:ZDB-GENE-050419-153
See related
Ensembl:ENSDARG00000015399 AllianceGenome:ZFIN:ZDB-GENE-050419-153
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:158301; si:dkey-199i24.2
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within sprouting angiogenesis. Predicted to be active in nucleus. Is expressed in gut; head; swim bladder; and swim bladder bud. Human ortholog(s) of this gene implicated in persistent fetal circulation syndrome. Orthologous to human FOXF1 (forkhead box F1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See foxf1 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (30847237..30851101)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (30868983..30872847)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488296 Neighboring gene uncharacterized LOC108180013 Neighboring gene uncharacterized LOC137488297 Neighboring gene methenyltetrahydrofolate synthetase domain containing

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Clone Names

  • MGC158301

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within sprouting angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080186.1NP_001073655.1  forkhead box protein F1

    See identical proteins and their annotated locations for NP_001073655.1

    Status: PROVISIONAL

    Source sequence(s)
    BC129194
    UniProtKB/Swiss-Prot
    A1L1S5
    Related
    ENSDARP00000022888.8, ENSDART00000012374.9
    Conserved Domains (1) summary
    smart00339
    Location:52140
    FH; FORKHEAD

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    30847237..30851101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)