slc6a2 solute carrier family 6 member 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc6a2provided by ZNC
Official Full Name: solute carrier family 6 member 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-110408-4
See related: Ensembl:ENSDARG00000016141 AllianceGenome:ZFIN:ZDB-GENE-110408-4
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:dkey-182h7.3
Summary: Predicted to enable dopamine:sodium symporter activity and norepinephrine:sodium symporter activity. Predicted to be involved in amino acid transport; catecholamine transport; and sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in axon; neuronal cell body membrane; and presynaptic membrane. Human ortholog(s) of this gene implicated in alcohol dependence; hypertension; and neurocirculatory asthenia. Orthologous to human SLC6A2 (solute carrier family 6 member 2). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (35348469..35380504, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (35080030..35109099, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables dopamine:sodium symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables norepinephrine:sodium symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables symporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in amino acid transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in dopamine uptake involved in synaptic transmission	IBA Inferred from Biological aspect of Ancestor more info
involved_in norepinephrine transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in sodium ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in axon	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in neuronal cell body membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in presynaptic membrane	IBA Inferred from Biological aspect of Ancestor more info