bend3 BEN domain containing 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: bend3provided by ZNC
Official Full Name: BEN domain containing 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-090312-181
See related: Ensembl:ENSDARG00000076903 AllianceGenome:ZFIN:ZDB-GENE-090312-181
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-206k20.6
Summary: Predicted to enable rDNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and rDNA heterochromatin formation. Predicted to be located in heterochromatin. Orthologous to human BEND3 (BEN domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (32641540..32648416, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (32511090..32517966, complement)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc21d12.x1 (e-PCR)
- UniSTS:193050

fc21d12.x1 (e-PCR)
- UniSTS:193051

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables rDNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in rDNA heterochromatin formation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within rDNA heterochromatin formation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in heterochromatin	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: BEN domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001145591.1 → NP_001139063.1 BEN domain-containing protein 3

Status: PROVISIONAL

Source sequence(s)

AL935163

UniProtKB/TrEMBL

A0A8M1NQ46, B7ZD94

Related

ENSDARP00000120361.1, ENSDART00000132820.3

Conserved Domains (1) summary

smart01025
Location:720 → 799

BEN; The BEN domain is found in diverse animal proteins