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znf827 zinc finger protein 827 [ Danio rerio (zebrafish) ]

Gene ID: 565077, updated on 2-Nov-2024

Summary

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Official Symbol
znf827provided by ZNC
Official Full Name
zinc finger protein 827provided by ZNC
Primary source
ZFIN:ZDB-GENE-080728-3
See related
Ensembl:ENSDARG00000076171 AllianceGenome:ZFIN:ZDB-GENE-080728-3
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-215c3.2
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF827 (zinc finger protein 827). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See znf827 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (36017856..36151419, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (35285833..35420008, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene metabolism of cobalamin associated A Neighboring gene zgc:152968 Neighboring gene LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene uncharacterized LOC137495596

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. An intestinal cell type in zebrafish is the nexus for the SARS-CoV-2 receptor and the Renin-Angiotensin-Aldosterone System that contributes to COVID-19 comorbidities. Postlethwait JH, et al. bioRxiv, 2020 Sep 2. PMID 32908984, Free PMC Article
  2. The SARS-CoV-2 receptor and other key components of the Renin-Angiotensin-Aldosterone System related to COVID-19 are expressed in enterocytes in larval zebrafish. Postlethwait JH, et al. Biol Open, 2021 Mar 23. PMID 33757938, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 827

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    36017856..36151419 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009292558.4 → XP_009290833.1  zinc finger protein 827 isoform X3

    UniProtKB/TrEMBL
    A0A8M3ATR1
    Conserved Domains (3) summary
    COG5048
    Location:409 → 483
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:430 → 450
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:1191 → 1215
    zf-H2C2_2; Zinc-finger double domain

  2. XM_001919166.8 → XP_001919201.4  zinc finger protein 827 isoform X2

    UniProtKB/TrEMBL
    A0A8M1QK95
    Conserved Domains (5) summary
    COG5048
    Location:409 → 483
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:430 → 450
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:875 → 895
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam05605
    Location:871 → 923
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
    pfam13465
    Location:1194 → 1218
    zf-H2C2_2; Zinc-finger double domain

  3. XM_005159977.5 → XP_005160034.1  zinc finger protein 827 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B762
    Conserved Domains (5) summary
    COG5048
    Location:409 → 483
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:430 → 450
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:875 → 895
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam05605
    Location:871 → 923
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
    pfam13465
    Location:1204 → 1228
    zf-H2C2_2; Zinc-finger double domain

  4. XM_005159980.5 → XP_005160037.1  zinc finger protein 827 isoform X4

    See identical proteins and their annotated locations for XP_005160037.1

    UniProtKB/TrEMBL
    A0A8M2B6U3, F1RA62
    Related
    ENSDARP00000154084.1, ENSDART00000182113.1
    Conserved Domains (5) summary
    COG5048
    Location:409 → 483
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:430 → 450
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:875 → 895
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam05605
    Location:871 → 923
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
    pfam13465
    Location:442 → 467
    zf-H2C2_2; Zinc-finger double domain

  5. XM_005159979.5 → XP_005160036.1  zinc finger protein 827 isoform X4

    See identical proteins and their annotated locations for XP_005160036.1

    UniProtKB/TrEMBL
    A0A8M2B6U3, F1RA62
    Related
    ENSDARP00000029203.7, ENSDART00000037516.9
    Conserved Domains (5) summary
    COG5048
    Location:409 → 483
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:430 → 450
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:875 → 895
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam05605
    Location:871 → 923
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
    pfam13465
    Location:442 → 467
    zf-H2C2_2; Zinc-finger double domain

  6. XM_068221441.1 → XP_068077542.1  zinc finger protein 827 isoform X5

    Related
    ENSDARP00000154333.1, ENSDART00000182904.1
Nucleotide Protein Strain
Heading Accession and Version

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