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cep78 centrosomal protein 78 [ Danio rerio (zebrafish) ]

Gene ID: 564741, updated on 2-Nov-2024

Summary

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Official Symbol
cep78provided by ZNC
Official Full Name
centrosomal protein 78provided by ZNC
Primary source
ZFIN:ZDB-GENE-070905-1
See related
Ensembl:ENSDARG00000039229 AllianceGenome:ZFIN:ZDB-GENE-070905-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to be involved in cilium organization. Predicted to be active in centrosome and ciliary basal body. Orthologous to human CEP78 (centrosomal protein 78). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See cep78 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (51935030..51954534, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (51949551..51968032, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene T-box transcription factor 16 Neighboring gene calcineurin binding protein 1 Neighboring gene guanine nucleotide binding protein (G protein), alpha 14a Neighboring gene vacuolar protein sorting 13 homolog A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in cilium organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
centrosomal protein of 78 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    51935030..51954534 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_688072.8 → XP_693164.4  centrosomal protein of 78 kDa isoform X2

    UniProtKB/TrEMBL
    A0A8N7TF73
    Conserved Domains (3) summary
    cd00116
    Location:12 → 293
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:101 → 125
    LRR_AMN1; leucine-rich repeat [structural motif]
    cl19252
    Location:419 → 536
    MreC; rod shape-determining protein MreC

  2. XM_009304317.4 → XP_009302592.1  centrosomal protein of 78 kDa isoform X1

    UniProtKB/TrEMBL
    A0A8M3AVK7, F1Q543
    Related
    ENSDARP00000057314.3, ENSDART00000057315.5
    Conserved Domains (3) summary
    cd00116
    Location:12 → 293
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00034
    Location:101 → 125
    LRR_AMN1; leucine-rich repeat [structural motif]
    cl19252
    Location:425 → 542
    MreC; rod shape-determining protein MreC
Nucleotide Protein Strain
Heading Accession and Version

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