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kif5ba kinesin family member 5B, a [ Danio rerio (zebrafish) ]

Gene ID: 563459, updated on 2-Nov-2024

Summary

Official Symbol
kif5baprovided by ZNC
Official Full Name
kinesin family member 5B, aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070629-2
See related
Ensembl:ENSDARG00000074131 AllianceGenome:ZFIN:ZDB-GENE-070629-2
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-159p3.5
Summary
Predicted to enable ATP hydrolysis activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Acts upstream of or within germ cell development; skeletal muscle tissue development; and skeletal system development. Predicted to be located in cytoskeleton. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm and microtubule. Is expressed in several structures, including central nervous system; digestive system; eye; pleuroperitoneal region; and trigeminal placode. Orthologous to human KIF5B (kinesin family member 5B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See kif5ba in Genome Data Viewer
Location:
chromosome: 2
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (43704097..43739529, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (43851099..43886575, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene NACHT, LRR and PYD domains-containing protein 1 homolog Neighboring gene NACHT, LRR and PYD domains-containing protein 3-like Neighboring gene dual specificity protein phosphatase 14 Neighboring gene Rho GTPase activating protein 12a Neighboring gene finTRIM family, member 16

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule motor activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables plus-end-directed microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in anterograde dendritic transport of neurotransmitter receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within bone morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within cartilage development IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within germ cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within microtubule-based movement IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within skeletal muscle tissue development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in synaptic vesicle transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
part_of kinesin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    43704097..43739529 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_686820.10XP_691912.6  kinesin-1 heavy chain isoform X2

    UniProtKB/TrEMBL
    A0A8N7UUZ8, F1R5M2
    Related
    ENSDARP00000104118.2, ENSDART00000113849.4
    Conserved Domains (5) summary
    smart00129
    Location:9332
    KISc; Kinesin motor, catalytic domain. ATPase
    cd01369
    Location:6325
    KISc_KHC_KIF5; Kinesin motor domain, kinesin heavy chain (KHC) or KIF5-like subgroup
    pfam05010
    Location:474678
    TACC; Transforming acidic coiled-coil-containing protein (TACC)
    pfam07851
    Location:602690
    TMPIT; TMPIT-like protein
    pfam14235
    Location:467536
    DUF4337; Domain of unknown function (DUF4337)
  2. XM_005171408.5XP_005171465.1  kinesin-1 heavy chain isoform X1

    UniProtKB/TrEMBL
    A0A8M2BJ79
    Conserved Domains (6) summary
    smart00129
    Location:9332
    KISc; Kinesin motor, catalytic domain. ATPase
    COG5281
    Location:305569
    COG5281; Phage-related minor tail protein [Mobilome: prophages, transposons]
    cd01369
    Location:6325
    KISc_KHC_KIF5; Kinesin motor domain, kinesin heavy chain (KHC) or KIF5-like subgroup
    pfam05010
    Location:474679
    TACC; Transforming acidic coiled-coil-containing protein (TACC)
    pfam07851
    Location:603691
    TMPIT; TMPIT-like protein
    pfam14235
    Location:467536
    DUF4337; Domain of unknown function (DUF4337)