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mxd4 MAX dimerization protein 4 [ Danio rerio (zebrafish) ]

Gene ID: 559531, updated on 17-Sep-2024

Summary

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Official Symbol
mxd4provided by ZNC
Official Full Name
MAX dimerization protein 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-050208-44
See related
Ensembl:ENSDARG00000054031 AllianceGenome:ZFIN:ZDB-GENE-050208-44
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mad4; im:7136512; si:ch211-145b13.8
Summary
Predicted to enable protein dimerization activity. Is expressed in head mesenchyme; notochord; pronephric duct; and pronephric mesoderm. Orthologous to human MXD4 (MAX dimerization protein 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See mxd4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (26071869..26097367)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (25378145..25403648)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene G patch domain and ankyrin repeats 1 Neighboring gene programmed cell death 4a Neighboring gene NADH:ubiquinone oxidoreductase subunit B Neighboring gene topoisomerase I binding, arginine/serine-rich a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Downregulation of Max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice. Shimada Y, et al. Int J Obes (Lond), 2014 Aug. PMID 24254064
  2. Phylogenetic analysis of zebrafish basic helix-loop-helix transcription factors. Wang Y, et al. J Mol Evol, 2009 Jun. PMID 19449054
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
max dimerization protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    26071869..26097367
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_682878.10 → XP_687970.6  max dimerization protein 4

    UniProtKB/TrEMBL
    A0A8N7TET9, E7F6Q1
    Related
    ENSDARP00000059263.5, ENSDART00000059264.6
    Conserved Domains (1) summary
    smart00353
    Location:58 → 110
    HLH; helix loop helix domain
Nucleotide Protein Strain
Heading Accession and Version

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