gnpda2 glucosamine-6-phosphate deaminase 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gnpda2provided by ZNC
Official Full Name: glucosamine-6-phosphate deaminase 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-091117-41
See related: Ensembl:ENSDARG00000024443 AllianceGenome:ZFIN:ZDB-GENE-091117-41
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:dkey-185e18.2
Summary: Predicted to enable glucosamine-6-phosphate deaminase activity and identical protein binding activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process and amino sugar catabolic process. Predicted to act upstream of or within N-acetylglucosamine metabolic process and carbohydrate metabolic process. Predicted to be active in cytoplasm. Orthologous to several human genes including GNPDA2 (glucosamine-6-phosphate deaminase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (4276400..4291182)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (4169378..4182721)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Involvement of Glucosamine 6 Phosphate Isomerase 2 (GNPDA2) Overproduction in beta-Amyloid- and Tau P301L-Driven Pathomechanisms.
Title: Involvement of Glucosamine 6 Phosphate Isomerase 2 (GNPDA2) Overproduction in β-Amyloid- and Tau P301L-Driven Pathomechanisms.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables glucosamine-6-phosphate deaminase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glucosamine-6-phosphate deaminase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables isomerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in N-acetylglucosamine catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within N-acetylglucosamine metabolic process	IEA Inferred from Electronic Annotation more info
involved_in N-acetylneuraminate catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in glucosamine catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain