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aoc1 amine oxidase copper containing 1 [ Danio rerio (zebrafish) ]

Gene ID: 555401, updated on 18-Sep-2024

Summary

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Official Symbol
aoc1provided by ZNC
Official Full Name
amine oxidase copper containing 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-061103-112
See related
Ensembl:ENSDARG00000061355 AllianceGenome:ZFIN:ZDB-GENE-061103-112
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
abp1; zgc:154101; si:ch211-286c5.2
Summary
Predicted to enable copper ion binding activity; diamine oxidase activity; and primary amine oxidase activity. Predicted to be involved in amine metabolic process and response to antibiotic. Predicted to be active in plasma membrane. Is expressed in ventral habenular nucleus. Orthologous to human AOC1 (amine oxidase copper containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human all
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Genomic context

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See aoc1 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (40001290..40009419, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (40113443..40121572, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100005038 Neighboring gene uncharacterized LOC100005096 Neighboring gene SCO-spondin Neighboring gene potassium voltage-gated channel, subfamily H (eag-related), member 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The habenulo-raphe serotonergic circuit encodes an aversive expectation value essential for adaptive active avoidance of danger. Amo R, et al. Neuron, 2014 Dec 3. PMID 25467985
  2. Liver toxicity of macrolide antibiotics in zebrafish. Zhang MQ, et al. Toxicology, 2020 Aug. PMID 32454074
  3. Identification of the zebrafish ventral habenula as a homolog of the mammalian lateral habenula. Amo R, et al. J Neurosci, 2010 Jan 27. PMID 20107084, Free PMC Article
  4. Neurotransmitter map of the asymmetric dorsal habenular nuclei of zebrafish. deCarvalho TN, et al. Genesis, 2014 Jun. PMID 24753112, Free PMC Article
  5. Dbx1b defines the dorsal habenular progenitor domain in the zebrafish epithalamus. Dean BJ, et al. Neural Dev, 2014 Sep 12. PMID 25212830, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC154101

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables copper ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables copper ion binding IEA
Inferred from Electronic Annotation
more info
  
enables diamine oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor IEA
Inferred from Electronic Annotation
more info
  
enables primary methylamine oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables primary methylamine oxidase activity IEA
Inferred from Electronic Annotation
more info
  
enables quinone binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within amine metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
diamine oxidase [copper-containing]
Names
amiloride binding protein 1 (amine oxidase (copper-containing))
dao
diamine oxidase
histaminase
NP_001071066.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077598.1 → NP_001071066.1  diamine oxidase [copper-containing] precursor

    See identical proteins and their annotated locations for NP_001071066.1

    Status: PROVISIONAL

    Source sequence(s)
    BC125956
    UniProtKB/TrEMBL
    A0A8N7UYD6, A0JMP5
    Related
    ENSDARP00000081856.4, ENSDART00000087422.5
    Conserved Domains (3) summary
    pfam01179
    Location:290 → 702
    Cu_amine_oxid; Copper amine oxidase, enzyme domain
    pfam02727
    Location:35 → 124
    Cu_amine_oxidN2; Copper amine oxidase, N2 domain
    pfam02728
    Location:140 → 239
    Cu_amine_oxidN3; Copper amine oxidase, N3 domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    40001290..40009419 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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