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TYRP1 tyrosinase related protein 1 [ Felis catus (domestic cat) ]

Gene ID: 554339, updated on 17-Aug-2024

Summary

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Official Symbol
TYRP1
Official Full Name
tyrosinase related protein 1
Primary source
VGNC:VGNC:82317
See related
EnsemblRapid:ENSFCTG00005011241
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Also known as
TRP; TRP1; TRP-1
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See TYRP1 in Genome Data Viewer
Location:
chromosome: D4
Exon count:
7
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) D4 NC_058380.1 (38129829..38148710)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) D4 NC_018735.3 (40068827..40087673)

Chromosome D4 - NC_058380.1Genomic Context describing neighboring genes Neighboring gene proteasome subunit alpha type-7-like Neighboring gene uncharacterized protein C6orf136 homolog Neighboring gene leucine rich adaptor protein 1 like Neighboring gene uncharacterized LOC109493796

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Chocolate coated cats: TYRP1 mutations for brown color in domestic cats. Lyons LA, et al. Mamm Genome, 2005 May. PMID 16104383
  2. Tyrosinase and tyrosinase related protein 1 alleles specify domestic cat coat color phenotypes of the albino and brown loci. Schmidt-Küntzel A, et al. J Hered, 2005 Jul-Aug. PMID 15858157
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. nucleotide variants of TYRP1 (chromosome D4) as specifying the chocolate (b) and cinnamon (b(l)) alleles of the B locus in determining cat hair color.
    Title: Tyrosinase and tyrosinase related protein 1 alleles specify domestic cat coat color phenotypes of the albino and brown loci.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in melanocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in melanosome organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in melanosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5,6-dihydroxyindole-2-carboxylic acid oxidase
Names
DHICA oxidase
NP_001036025.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042560.2 → NP_001036025.2  5,6-dihydroxyindole-2-carboxylic acid oxidase precursor

    See identical proteins and their annotated locations for NP_001036025.2

    Status: PROVISIONAL

    Source sequence(s)
    AY956310
    UniProtKB/Swiss-Prot
    Q2VPU6, Q2VPU7, Q2VPU8, Q2VPW6, Q4VNX7, Q4VNX8
    UniProtKB/TrEMBL
    M3WPS0
    Related
    ENSFCTP00005020718.1, ENSFCTT00005031464.1
    Conserved Domains (1) summary
    pfam00264
    Location:183 → 417
    Tyrosinase; Common central domain of tyrosinase

RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058380.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    38129829..38148710
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2VPW6.1 GenPept UniProtKB/Swiss-Prot:Q2VPW6

Gene LinkOut

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