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paplnb papilin b, proteoglycan-like sulfated glycoprotein [ Danio rerio (zebrafish) ]

Gene ID: 553586, updated on 2-Nov-2024

Summary

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Official Symbol
paplnbprovided by ZNC
Official Full Name
papilin b, proteoglycan-like sulfated glycoproteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6023
See related
Ensembl:ENSDARG00000042186 AllianceGenome:ZFIN:ZDB-GENE-030131-6023
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
papln; wu:fi31b03; zgc:110061; si:dkey-65b13.4
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to act upstream of or within extracellular matrix organization. Predicted to be located in extracellular region. Orthologous to human PAPLN (papilin, proteoglycan like sulfated glycoprotein). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See paplnb in Genome Data Viewer
Location:
chromosome: 20
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (33499374..33512459, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (33596495..33609794, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene SMEK homolog 1, suppressor of mek1 (Dictyostelium) Neighboring gene uncharacterized LOC137488669 Neighboring gene ERH mRNA splicing and mitosis factor Neighboring gene dynein regulatory complex subunit 1 homolog (Chlamydomonas) Neighboring gene potassium voltage-gated channel, subfamily F, member 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The evolution of the vertebrate metzincins; insights from Ciona intestinalis and Danio rerio. Huxley-Jones J, et al. BMC Evol Biol, 2007 Apr 17. PMID 17439641, Free PMC Article
  2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC110061

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
papilin b, proteoglycan-like sulfated glycoprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020564.1 → NP_001018400.1  papilin b, proteoglycan-like sulfated glycoprotein precursor

    See identical proteins and their annotated locations for NP_001018400.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095166
    UniProtKB/TrEMBL
    Q503V4
    Related
    ENSDARP00000061835.5, ENSDART00000061836.8
    Conserved Domains (2) summary
    smart00209
    Location:28 → 78
    TSP1; Thrombospondin type 1 repeats
    pfam00014
    Location:470 → 522
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    33499374..33512459 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005160691.5 → XP_005160748.1  papilin b, proteoglycan-like sulfated glycoprotein isoform X1

    UniProtKB/TrEMBL
    A0A8M2B7L3
    Conserved Domains (2) summary
    smart00209
    Location:28 → 78
    TSP1; Thrombospondin type 1 repeats
    pfam00014
    Location:460 → 512
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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