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crybb2 crystallin, beta B2 [ Danio rerio (zebrafish) ]

Gene ID: 553182, updated on 2-Nov-2024

Summary

Official Symbol
crybb2provided by ZNC
Official Full Name
crystallin, beta B2provided by ZNC
Primary source
ZFIN:ZDB-GENE-060130-1
See related
Ensembl:ENSDARG00000053512 AllianceGenome:ZFIN:ZDB-GENE-060130-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Is expressed in eye and lens. Human ortholog(s) of this gene implicated in cataract and cataract 3 multiple types. Orthologous to human CRYBB2 (crystallin beta B2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See crybb2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (42629733..42636275)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (42622946..42629488)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene docking protein 2 Neighboring gene Kazal-type serine peptidase inhibitor domain 3 Neighboring gene si:ch73-138n13.1 Neighboring gene zgc:194007

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural constituent of eye lens IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in lens development in camera-type eye IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in visual perception IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
beta-crystallin B2
Names
beta B2-crystallin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001018128.1NP_001018138.1  beta-crystallin B2

    See identical proteins and their annotated locations for NP_001018138.1

    Status: PROVISIONAL

    Source sequence(s)
    BC154625
    UniProtKB/TrEMBL
    A8WG93, Q52JI4
    Related
    ENSDARP00000070035.3, ENSDART00000075553.5
    Conserved Domains (1) summary
    pfam00030
    Location:111193
    Crystall; Beta/Gamma crystallin

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    42629733..42636275
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)