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plxnb2 plexin B2 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 550076, updated on 4-Nov-2024

Summary

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Official Symbol
plxnb2provided by Xenbase
Official Full Name
plexin B2provided by Xenbase
Primary source
Xenbase:XB-GENE-856509
See related
Ensembl:ENSXETG00000022253 AllianceGenome:Xenbase:XB-GENE-856509
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable semaphorin receptor activity. Predicted to act upstream of or within semaphorin-plexin signaling pathway. Predicted to be located in plasma membrane. Orthologous to human PLXNB2 (plexin B2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See plxnb2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
38
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (71410701..71521622)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (61841370..61952965)

Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105946844 Neighboring gene glutamate receptor, metabotropic 8 Neighboring gene zinc finger protein 800 Neighboring gene mitogen-activated protein kinase 11 Neighboring gene mitogen-activated protein kinase 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables semaphorin receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within semaphorin-plexin signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
plexin-B2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017322.4 → NP_001017322.3  plexin-B2 precursor

    Status: VALIDATED

    Source sequence(s)
    AAMC04000003
    UniProtKB/TrEMBL
    A0A6I8R895, A0A8J0PJH0
    Related
    ENSXETP00000078137.2, ENSXETT00000097223.2
    Conserved Domains (6) summary
    smart00423
    Location:632 → 670
    PSI; domain found in Plexins, Semaphorins and Integrins
    pfam01437
    Location:473 → 520
    PSI; Plexin repeat
    pfam08337
    Location:1266 → 1799
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain
    pfam17960
    Location:529 → 618
    TIG_plexin; TIG domain
    cl15674
    Location:805 → 894
    IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
    cl15693
    Location:25 → 472
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    71410701..71521622
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012959119.3 → XP_012814573.2  plexin-B2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8R895, A0A8J0PJH0
    Conserved Domains (6) summary
    smart00423
    Location:632 → 670
    PSI; domain found in Plexins, Semaphorins and Integrins
    pfam01437
    Location:473 → 520
    PSI; Plexin repeat
    pfam08337
    Location:1266 → 1799
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain
    pfam17960
    Location:529 → 618
    TIG_plexin; TIG domain
    cl15674
    Location:805 → 894
    IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
    cl15693
    Location:25 → 472
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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