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mgrn1 mahogunin ring finger 1, E3 ubiquitin protein ligase [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 549665, updated on 4-Nov-2024

Summary

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Official Symbol
mgrn1provided by Xenbase
Official Full Name
mahogunin ring finger 1, E3 ubiquitin protein ligaseprovided by Xenbase
Primary source
Xenbase:XB-GENE-963240
See related
Ensembl:ENSXETG00000047412 AllianceGenome:Xenbase:XB-GENE-963240
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable metal ion binding activity and ubiquitin protein ligase activity. Predicted to act upstream of or within protein ubiquitination. Predicted to be located in cytoplasm. Is expressed in mesoderm; musculoskeletal system; nervous system; and pharyngeal arch. Orthologous to human MGRN1 (mahogunin ring finger 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See mgrn1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
17
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (199401..216925, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683708.1 (1..5707)

Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene adenine nucleotide translocase lysine methyltransferase Neighboring gene coiled-coil domain containing 78 Neighboring gene insulin like growth factor binding protein acid labile subunit Neighboring gene chromosome 9 C16orf96 homolog Neighboring gene cell death-inducing p53 target 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC147719

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
E3 ubiquitin-protein ligase MGRN1
Names
mahogunin, ring finger 1
NP_001016911.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001016911.3 → NP_001016911.1  E3 ubiquitin-protein ligase MGRN1

    Status: PROVISIONAL

    Source sequence(s)
    CR848375
    UniProtKB/TrEMBL
    A0A803JUZ9, A0A8J0PJ16
    Related
    ENSXETP00000111840.1, ENSXETT00000122877.1
    Conserved Domains (2) summary
    PHA02929
    Location:230 → 329
    PHA02929; N1R/p28-like protein; Provisional
    pfam13920
    Location:272 → 317
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    199401..216925 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001113096.1: Suppressed sequence

    Description
    NM_001113096.1: This RefSeq was permanently suppressed because there is no support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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