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abca8 ATP binding cassette subfamily A member 8 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 549630, updated on 4-Nov-2024

Summary

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Official Symbol
abca8provided by Xenbase
Official Full Name
ATP binding cassette subfamily A member 8provided by Xenbase
Primary source
Xenbase:XB-GENE-1005441
See related
Ensembl:ENSXETG00000021959 AllianceGenome:Xenbase:XB-GENE-1005441
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
abca8a
Summary
Predicted to enable ABC-type transporter activity; ATP binding activity; and ATP hydrolysis activity. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Orthologous to several human genes including ABCA10 (ATP binding cassette subfamily A member 10); ABCA6 (ATP binding cassette subfamily A member 6); and ABCA8 (ATP binding cassette subfamily A member 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See abca8 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
41
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 10 NC_030686.2 (31433237..31496572, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 10 NC_030686.1 (23312643..23323415, complement)

Chromosome 10 - NC_030686.2Genomic Context describing neighboring genes Neighboring gene phosphatidylglycerophosphate synthase 1 Neighboring gene ATP binding cassette subfamily A member 10 Neighboring gene uncharacterized LOC116407967 Neighboring gene ATP binding cassette subfamily A member 5 Neighboring gene BTB (POZ) domain containing 17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ATP binding cassette subfamily A member 8
Names
ATP-binding cassette, sub-family A (ABC1), member 8
ATP-binding cassette, sub-family A (ABC1), member 8a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001016876.2 → NP_001016876.1  ATP binding cassette subfamily A member 8

    Status: PROVISIONAL

    Source sequence(s)
    CR848608
    UniProtKB/TrEMBL
    B5DFP6, K9J852
    Related
    ENSXETP00000028045.4, ENSXETT00000028045.5
    Conserved Domains (2) summary
    cd03263
    Location:1 → 179
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
    COG1131
    Location:1 → 270
    CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030686.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    31433237..31496572 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031894111.1 → XP_031749971.1  ATP binding cassette subfamily A member 8 isoform X1

    UniProtKB/TrEMBL
    A0A8J1IWJ6
    Conserved Domains (1) summary
    TIGR01257
    Location:225 → 1601
    rim_protein; retinal-specific rim ABC transporter

  2. XM_031894112.1 → XP_031749972.1  ATP binding cassette subfamily A member 8 isoform X1

    UniProtKB/TrEMBL
    A0A8J1IWJ6
    Conserved Domains (1) summary
    TIGR01257
    Location:225 → 1601
    rim_protein; retinal-specific rim ABC transporter

  3. XM_031894113.1 → XP_031749973.1  ATP binding cassette subfamily A member 8 isoform X1

    UniProtKB/TrEMBL
    A0A8J1IWJ6
    Conserved Domains (1) summary
    TIGR01257
    Location:225 → 1601
    rim_protein; retinal-specific rim ABC transporter
Nucleotide Protein Strain
Heading Accession and Version

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