gtf2e2 general transcription factor IIE subunit 2 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: gtf2e2provided by Xenbase
Official Full Name: general transcription factor IIE subunit 2provided by Xenbase
Primary source: Xenbase:XB-GENE-962385
See related: Ensembl:ENSXETG00000011291 AllianceGenome:Xenbase:XB-GENE-962385
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: tf2e2; tfiie-b; TFIIE-beta
Summary: Predicted to enable DNA binding activity. Predicted to act upstream of or within transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIE complex. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 6. Orthologous to human GTF2E2 (general transcription factor IIE subunit 2). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	1	NC_030677.2 (83791507..83814754)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	1	NC_030677.1 (90074988..90096468)

Chromosome 1 - NC_030677.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within transcription initiation at RNA polymerase II promoter	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIIE complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: transcription initiation factor IIE subunit beta

Names: general transcription factor IIE, polypeptide 2, beta 34kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001016555.2 → NP_001016555.1 transcription initiation factor IIE subunit beta

See identical proteins and their annotated locations for NP_001016555.1

Status: PROVISIONAL

Source sequence(s)

CR760710

UniProtKB/TrEMBL

A0A6I8QW63, F7A2K2, L7N340, Q28HW0

Related

ENSXETP00000024636.4, ENSXETT00000024636.4

Conserved Domains (2) summary

cd07977
Location:65 → 143

TFIIE_beta_winged_helix; TFIIE_beta_winged_helix domain, located at the central core region of TFIIE beta, with double-stranded DNA binding activity

pfam18121
Location:143 → 201

TFA2_Winged_2; TFA2 Winged helix domain 2