zgpat zinc finger, CCCH-type with G-patch domain [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: zgpatprovided by Xenbase
Official Full Name: zinc finger, CCCH-type with G-patch domainprovided by Xenbase
Primary source: Xenbase:XB-GENE-6257472
See related: Ensembl:ENSXETG00000047354 AllianceGenome:Xenbase:XB-GENE-6257472
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: zc3h9; gpatc6; gpatch6; zc3hdc9
Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of DNA-templated transcription and negative regulation of epidermal growth factor-activated receptor activity. Predicted to be active in nucleus. Is expressed in ectoderm; musculoskeletal system; nervous system; pharyngeal arch; and visual system. Orthologous to human ZGPAT (zinc finger CCCH-type and G-patch domain containing). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	10	NC_030686.2 (1072857..1101037)

Chromosome 10 - NC_030686.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_030686.2 Chromosome 10 Reference UCB_Xtro_10.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of DNA-templated transcription	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within negative regulation of epidermal growth factor-activated receptor activity	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: zinc finger CCCH-type with G patch domain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001016444.2 → NP_001016444.1 zinc finger CCCH-type with G patch domain-containing protein

See identical proteins and their annotated locations for NP_001016444.1

Status: PROVISIONAL

Source sequence(s)

CR761014

UniProtKB/Swiss-Prot

B3DL93, Q28H71

Related

ENSXETP00000105804.1, ENSXETT00000121621.1

Conserved Domains (3) summary

cd04508
Location:217 → 247

TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...

smart00356
Location:173 → 195

ZnF_C3H1; zinc finger

pfam01585
Location:315 → 356

G-patch; G-patch domain

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030686.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

1072857..1101037

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_031894085.1 → XP_031749945.1 zinc finger CCCH-type with G patch domain-containing protein isoform X1

UniProtKB/TrEMBL

A0A803JG04

Related

ENSXETP00000106814.1, ENSXETT00000121016.1

Conserved Domains (3) summary

pfam01585
Location:317 → 359

G-patch; G-patch domain

pfam18044
Location:178 → 198

zf-CCCH_4; CCCH-type zinc finger

cd20384
Location:214 → 268

Tudor_ZGPAT; Tudor domain found in zinc finger CCCH-type with G patch domain-containing protein (ZGPAT) and similar proteins