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rbp4 retinol binding protein 4 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 548465, updated on 4-Nov-2024

Summary

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Official Symbol
rbp4provided by Xenbase
Official Full Name
retinol binding protein 4provided by Xenbase
Primary source
Xenbase:XB-GENE-5841608
See related
Ensembl:ENSXETG00000003731 AllianceGenome:Xenbase:XB-GENE-5841608
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
srbp
Summary
Predicted to enable retinol binding activity. Predicted to be involved in retinol transport. Predicted to act upstream of or within liver development and response to retinoic acid. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in coronary artery disease and type 2 diabetes mellitus. Orthologous to human RBP4 (retinol binding protein 4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See rbp4 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
6
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 7 NC_030683.2 (35996040..36005264, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 7 NC_030683.1 (27749813..27759032, complement)

Chromosome 7 - NC_030683.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116412304 Neighboring gene centrosomal protein 55kDa Neighboring gene free fatty acid receptor 4 Neighboring gene phosphodiesterase 6C Neighboring gene fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC107934

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables retinoid binding IEA
Inferred from Electronic Annotation
more info
  
enables retinol binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables retinol binding IEA
Inferred from Electronic Annotation
more info
  
enables retinol transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within liver development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to retinoic acid IEA
Inferred from Electronic Annotation
more info
  
involved_in retinol transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
retinol-binding protein 4
Names
retinol binding protein 4, plasma
serum retinol binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001015748.1 → NP_001015748.1  retinol-binding protein 4 precursor

    See identical proteins and their annotated locations for NP_001015748.1

    Status: PROVISIONAL

    Source sequence(s)
    BC089684
    UniProtKB/TrEMBL
    F6UH11, Q5EBG1
    Related
    ENSXETP00000008077.3, ENSXETT00000008077.5
    Conserved Domains (1) summary
    cl10502
    Location:24 → 195
    lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    35996040..36005264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031905052.1 → XP_031760912.1  retinol-binding protein 4 isoform X1

    UniProtKB/TrEMBL
    F6UH11, Q5EBG1
    Conserved Domains (1) summary
    cl10502
    Location:24 → 195
    lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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