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LEFTY2 left-right determination factor 2 [ Bos taurus (domestic cattle) ]

Gene ID: 534018, updated on 4-Oct-2024

Summary

Gene symbol
LEFTY2
Gene description
left-right determination factor 2
See related
BGD:BT11565; Ensembl:ENSBTAG00000058712
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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Genomic context

See LEFTY2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (28910505..28913354, complement)

Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene epoxide hydrolase 1 Neighboring gene transmembrane protein 63A Neighboring gene uncharacterized LOC112441822 Neighboring gene uncharacterized LOC112441823 Neighboring gene pyrroline-5-carboxylate reductase 2

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables transforming growth factor beta receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in SMAD protein signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
left-right determination factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206043.2NP_001192972.2  left-right determination factor 2 precursor

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000016
    UniProtKB/TrEMBL
    E1BBY0
    Related
    ENSBTAP00000049627.3, ENSBTAT00000051964.4
    Conserved Domains (2) summary
    pfam00019
    Location:264354
    TGF_beta; Transforming growth factor beta like domain
    pfam00688
    Location:99203
    TGFb_propeptide; TGF-beta propeptide

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    28910505..28913354 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)