U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LAMB2 laminin, beta 2 (laminin S) [ Bos taurus (domestic cattle) ]

Gene ID: 520167, updated on 4-Oct-2024

Summary

Go to the top of the page Help
Gene symbol
LAMB2
Gene description
laminin, beta 2 (laminin S)
See related
Ensembl:ENSBTAG00000022635
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See LAMB2 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (50883620..50897890)

Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene laminin subunit beta-2 Neighboring gene laminin subunit beta-2 Neighboring gene ubiquitin specific peptidase 19 Neighboring gene glutaminyl-tRNA synthetase 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC128643

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in basement membrane assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of laminin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
laminin subunit beta-2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001046247.2 → NP_001039712.2  laminin subunit beta-2 precursor

    Status: VALIDATED

    Source sequence(s)
    BC105436, CK963940, DT810209, DT811149, DV875815, DV920193, EE366453, EE385105, EH174117, EV706949
    UniProtKB/TrEMBL
    E1BDK6
    Related
    ENSBTAP00000051130.3, ENSBTAT00000057452.3
    Conserved Domains (7) summary
    smart00180
    Location:787 → 832
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:525 → 566
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1147 → 1186
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:61 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam12795
    Location:1482 → 1777
    MscS_porin; Mechanosensitive ion channel porin domain
    cl02193
    Location:1555 → 1744
    VirB5_like; VirB5 protein family
    cl21478
    Location:1457 → 1545
    ATP-synt_B; ATP synthase B/B' CF(0)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    50883620..50897890
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010817733.4 → XP_010816035.2  laminin subunit beta-2 isoform X1

    UniProtKB/TrEMBL
    E1BDK6
    Conserved Domains (5) summary
    smart00180
    Location:787 → 832
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:525 → 566
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1072 → 1111
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:65 → 285
    Laminin_N; Laminin N-terminal (Domain VI)
    cl25732
    Location:1127 → 1717
    SMC_N; RecF/RecN/SMC N terminal domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.