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CDK12 cyclin dependent kinase 12 [ Homo sapiens (human) ]

Gene ID: 51755, updated on 14-Nov-2024

Summary

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Official Symbol
CDK12provided by HGNC
Official Full Name
cyclin dependent kinase 12provided by HGNC
Primary source
HGNC:HGNC:24224
See related
Ensembl:ENSG00000167258 MIM:615514; AllianceGenome:HGNC:24224
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CRK7; CRKR; CRKRS
Summary
Enables RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in several processes, including positive regulation of transcription elongation by RNA polymerase II; protein autophosphorylation; and regulation of MAP kinase activity. Located in nuclear speck. Part of cyclin K-CDK12 complex. Biomarker of gastric adenocarcinoma; hepatocellular carcinoma; and stomach cancer. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis (RPKM 8.6), bone marrow (RPKM 8.1) and 25 other tissues See more
Orthologs
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Genomic context

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See CDK12 in Genome Data Viewer
Location:
17q12
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (39461486..39567559)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (40325392..40431128)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (37617739..37690797)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene F-box and leucine rich repeat protein 20 Neighboring gene microRNA 548BC Neighboring gene MPRA-validated peak2834 silencer Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:37489325-37489835 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:37493495-37494252 Neighboring gene Sharpr-MPRA regulatory region 12086 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:37557132-37557424 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8453 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8456 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8455 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8454 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:37558864-37559028 Neighboring gene mediator complex subunit 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr17:37618166-37619365 Neighboring gene U6 spliceosomal RNA Neighboring gene RNA, U6 small nuclear 233, pseudogene Neighboring gene uncharacterized LOC105371770 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8457 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:37730809-37731383 Neighboring gene uncharacterized LOC105371771

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. CDK12 Activity-Dependent Phosphorylation Events in Human Cells. Bartkowiak B, et al. Biomolecules, 2019 Oct 22. PMID 31652541, Free PMC Article
  2. CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma. Houles T, et al. Nat Commun, 2022 Oct 29. PMID 36309522, Free PMC Article
  3. CDK12 Is Necessary to Promote Epidermal Differentiation Through Transcription Elongation. Li J, et al. Stem Cells, 2022 Apr 29. PMID 35325240, Free PMC Article
  4. CDK12 activates MYC to repress miR-28-5p/EZH2 and amplifies tonic BCR signaling to promote the development of diffuse large B-cell lymphoma. Liu QH, et al. Cancer Gene Ther, 2022 Aug. PMID 35082399
  5. Predicted Immunogenicity of CDK12 Biallelic Loss-of-Function Tumors Varies across Cancer Types. Elliott A, et al. J Mol Diagn, 2021 Dec. PMID 34562615

See all (176) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Interaction of CDK12 with NXF1 is a new node for the linking mechanism between transcription and transportation of mRNA.
    Title: Interaction of CDK12 with NXF1 is a new node for the linking mechanism between transcription and transportation of mRNA.
  2. CDK12 is a promising therapeutic target for the transcription cycle and DNA damage response in metastatic osteosarcoma.
    Title: CDK12 is a promising therapeutic target for the transcription cycle and DNA damage response in metastatic osteosarcoma.
  3. Structure-independent machine-learning predictions of the CDK12 interactome.
    Title: Structure-independent machine-learning predictions of the CDK12 interactome.
  4. Tubule-specific cyclin-dependent kinase 12 knockdown potentiates kidney injury through transcriptional elongation defects.
    Title: Tubule-specific cyclin-dependent kinase 12 knockdown potentiates kidney injury through transcriptional elongation defects.
  5. Cyclin-dependent kinase 12 deficiency reprogrammes cellular metabolism to alleviate ferroptosis potential and promote the progression of castration-resistant prostate cancer.
    Title: Cyclin-dependent kinase 12 deficiency reprogrammes cellular metabolism to alleviate ferroptosis potential and promote the progression of castration-resistant prostate cancer.
  6. Analysis of Breast Cancer Brain Metastases Reveals an Enrichment of Cyclin-Dependent Kinase 12 Structural Rearrangements in Human Epidermal Growth Factor Receptor 2-Positive Disease.
    Title: Analysis of Breast Cancer Brain Metastases Reveals an Enrichment of Cyclin-Dependent Kinase 12 Structural Rearrangements in Human Epidermal Growth Factor Receptor 2-Positive Disease.
  7. ERBB2-amplified lobular breast carcinoma exhibits concomitant CDK12 co-amplification associated with poor prognostic features.
    Title: ERBB2-amplified lobular breast carcinoma exhibits concomitant CDK12 co-amplification associated with poor prognostic features.
  8. Trans-Regulation of Alternative PD-L1 mRNA Processing by CDK12 in Non-Small-Cell Lung Cancer Cells.
    Title: Trans-Regulation of Alternative PD-L1 mRNA Processing by CDK12 in Non-Small-Cell Lung Cancer Cells.
  9. Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release.
    Title: Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release.
  10. CDK12 Promotes the Proliferation, Migration, and Angiogenesis of Gastric Carcinoma via Activating the PI3K/AKT/mTOR Signaling Pathway.
    Title: CDK12 Promotes the Proliferation, Migration, and Angiogenesis of Gastric Carcinoma via Activating the PI3K/AKT/mTOR Signaling Pathway.
Submit: New GeneRIF Correction See all GeneRIFs (67)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA0904

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II CTD heptapeptide repeat S2 kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II CTD heptapeptide repeat S5 kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II CTD heptapeptide repeat S7 kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II CTD heptapeptide repeat T4 kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II CTD heptapeptide repeat Y1 kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II CTD heptapeptide repeat kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II CTD heptapeptide repeat kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA polymerase II CTD heptapeptide repeat kinase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables cyclin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cyclin binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
  
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in RNA splicing ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of stem cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription elongation by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of transcription elongation by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein autophosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of MAP kinase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of cyclin K-CDK12 complex IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of cyclin/CDK positive transcription elongation factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of nuclear cyclin-dependent protein kinase holoenzyme complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nuclear speck IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cyclin-dependent kinase 12
Names
CDC2-related protein kinase 7
Cdc2-related kinase, arginine/serine-rich
cell division cycle 2-related protein kinase 7
cell division protein kinase 12
NP_055898.1
NP_057591.2
XP_005257513.1
XP_011523195.1
XP_011523196.1
XP_011523197.1
XP_011523199.1
XP_011523200.1
XP_011523208.1
XP_011523209.1
XP_016880242.1
XP_047292209.1
XP_047292211.1
XP_047292212.1
XP_047292213.1
XP_047292214.1
XP_047292215.1
XP_047292216.1
XP_047292217.1
XP_047292218.1
XP_047292219.1
XP_047292220.1
XP_047292221.1
XP_047292222.1
XP_047292223.1
XP_047292224.1
XP_047292225.1
XP_047292226.1
XP_047292228.1
XP_047292229.1
XP_047292230.1
XP_047292231.1
XP_047292232.1
XP_047292233.1
XP_047292234.1
XP_047292235.1
XP_047292236.1
XP_047292237.1
XP_047292238.1
XP_047292239.1
XP_047292240.1
XP_047292241.1
XP_047292242.1
XP_047292243.1
XP_047292244.1
XP_047292245.1
XP_047292246.1
XP_047292247.1
XP_047292248.1
XP_047292249.1
XP_054172424.1
XP_054172425.1
XP_054172426.1
XP_054172427.1
XP_054172428.1
XP_054172429.1
XP_054172430.1
XP_054172431.1
XP_054172432.1
XP_054172433.1
XP_054172434.1
XP_054172435.1
XP_054172436.1
XP_054172437.1
XP_054172438.1
XP_054172439.1
XP_054172440.1
XP_054172441.1
XP_054172442.1
XP_054172443.1
XP_054172444.1
XP_054172445.1
XP_054172446.1
XP_054172447.1
XP_054172448.1
XP_054172449.1
XP_054172450.1
XP_054172451.1
XP_054172452.1
XP_054172453.1
XP_054172454.1
XP_054172455.1
XP_054172456.1
XP_054172457.1
XP_054172458.1
XP_054172459.1
XP_054172460.1
XP_054172461.1
XP_054172462.1
XP_054172463.1
XP_054172464.1
XP_054172465.1
XP_054172466.1
XP_054172467.1
XP_054172468.1
XP_054172469.1
XP_054172470.1
XP_054172471.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_065324.1 RefSeqGene

    Range
    5001..78059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_1413

mRNA and Protein(s)

  1. NM_015083.4 → NP_055898.1  cyclin-dependent kinase 12 isoform 2

    See identical proteins and their annotated locations for NP_055898.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
    Source sequence(s)
    AC009283, AK302645, BC150265, BE003756, BM557102
    Consensus CDS
    CCDS45666.1
    UniProtKB/TrEMBL
    J3QSD7
    Related
    ENSP00000407720.2, ENST00000430627.6
    Conserved Domains (2) summary
    smart00220
    Location:727 → 1020
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:719 → 1020
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  2. NM_016507.4 → NP_057591.2  cyclin-dependent kinase 12 isoform 1

    See identical proteins and their annotated locations for NP_057591.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform.
    Source sequence(s)
    AC009283, AF227198, AK302645, BC150265, BE003756, BM557102
    Consensus CDS
    CCDS11337.1
    UniProtKB/Swiss-Prot
    A7E2B2, B4DYX4, B9EIQ6, O94978, Q9NYV4
    UniProtKB/TrEMBL
    J3QSD7
    Related
    ENSP00000398880.4, ENST00000447079.6
    Conserved Domains (2) summary
    smart00220
    Location:727 → 1020
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:719 → 1020
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    39461486..39567559
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047436256.1 → XP_047292212.1  cyclin-dependent kinase 12 isoform X3

  2. XM_047436261.1 → XP_047292217.1  cyclin-dependent kinase 12 isoform X3

  3. XM_047436260.1 → XP_047292216.1  cyclin-dependent kinase 12 isoform X3

  4. XM_011524897.3 → XP_011523199.1  cyclin-dependent kinase 12 isoform X3

    See identical proteins and their annotated locations for XP_011523199.1

    UniProtKB/TrEMBL
    J3QSD7
    Conserved Domains (1) summary
    cd07864
    Location:719 → 1020
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  5. XM_047436255.1 → XP_047292211.1  cyclin-dependent kinase 12 isoform X3

  6. XM_011524895.3 → XP_011523197.1  cyclin-dependent kinase 12 isoform X3

    See identical proteins and their annotated locations for XP_011523197.1

    UniProtKB/TrEMBL
    J3QSD7
    Conserved Domains (1) summary
    cd07864
    Location:719 → 1020
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  7. XM_011524893.3 → XP_011523195.1  cyclin-dependent kinase 12 isoform X3

    See identical proteins and their annotated locations for XP_011523195.1

    UniProtKB/TrEMBL
    J3QSD7
    Conserved Domains (1) summary
    cd07864
    Location:719 → 1020
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  8. XM_011524894.3 → XP_011523196.1  cyclin-dependent kinase 12 isoform X3

    See identical proteins and their annotated locations for XP_011523196.1

    UniProtKB/TrEMBL
    J3QSD7
    Conserved Domains (1) summary
    cd07864
    Location:719 → 1020
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  9. XM_047436258.1 → XP_047292214.1  cyclin-dependent kinase 12 isoform X3

  10. XM_011524906.3 → XP_011523208.1  cyclin-dependent kinase 12 isoform X3

    See identical proteins and their annotated locations for XP_011523208.1

    UniProtKB/TrEMBL
    J3QSD7
    Conserved Domains (1) summary
    cd07864
    Location:719 → 1020
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  11. XM_047436259.1 → XP_047292215.1  cyclin-dependent kinase 12 isoform X3

  12. XM_011524898.3 → XP_011523200.1  cyclin-dependent kinase 12 isoform X3

    See identical proteins and their annotated locations for XP_011523200.1

    UniProtKB/TrEMBL
    J3QSD7
    Conserved Domains (1) summary
    cd07864
    Location:719 → 1020
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  13. XM_047436257.1 → XP_047292213.1  cyclin-dependent kinase 12 isoform X3

  14. XM_047436278.1 → XP_047292234.1  cyclin-dependent kinase 12 isoform X5

  15. XM_047436267.1 → XP_047292223.1  cyclin-dependent kinase 12 isoform X5

  16. XM_047436277.1 → XP_047292233.1  cyclin-dependent kinase 12 isoform X5

  17. XM_047436268.1 → XP_047292224.1  cyclin-dependent kinase 12 isoform X5

  18. XM_047436265.1 → XP_047292221.1  cyclin-dependent kinase 12 isoform X5

  19. XM_047436266.1 → XP_047292222.1  cyclin-dependent kinase 12 isoform X5

  20. XM_047436270.1 → XP_047292226.1  cyclin-dependent kinase 12 isoform X5

  21. XM_047436273.1 → XP_047292229.1  cyclin-dependent kinase 12 isoform X5

  22. XM_047436275.1 → XP_047292231.1  cyclin-dependent kinase 12 isoform X5

  23. XM_047436276.1 → XP_047292232.1  cyclin-dependent kinase 12 isoform X5

  24. XM_047436274.1 → XP_047292230.1  cyclin-dependent kinase 12 isoform X5

  25. XM_047436279.1 → XP_047292235.1  cyclin-dependent kinase 12 isoform X5

  26. XM_047436269.1 → XP_047292225.1  cyclin-dependent kinase 12 isoform X5

  27. XM_047436272.1 → XP_047292228.1  cyclin-dependent kinase 12 isoform X5

  28. XM_011524907.3 → XP_011523209.1  cyclin-dependent kinase 12 isoform X7

    UniProtKB/TrEMBL
    H0YLT2, J3QSD7
    Related
    ENSP00000453329.2, ENST00000559663.2
    Conserved Domains (2) summary
    smart00220
    Location:727 → 1020
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:719 → 1020
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  29. XM_047436287.1 → XP_047292243.1  cyclin-dependent kinase 12 isoform X7

    UniProtKB/TrEMBL
    H0YLT2

  30. XM_047436288.1 → XP_047292244.1  cyclin-dependent kinase 12 isoform X7

    UniProtKB/TrEMBL
    H0YLT2

  31. XM_047436289.1 → XP_047292245.1  cyclin-dependent kinase 12 isoform X7

    UniProtKB/TrEMBL
    H0YLT2

  32. XM_047436293.1 → XP_047292249.1  cyclin-dependent kinase 12 isoform X9

  33. XM_047436262.1 → XP_047292218.1  cyclin-dependent kinase 12 isoform X4

  34. XM_047436264.1 → XP_047292220.1  cyclin-dependent kinase 12 isoform X4

  35. XM_047436263.1 → XP_047292219.1  cyclin-dependent kinase 12 isoform X4

  36. XM_047436282.1 → XP_047292238.1  cyclin-dependent kinase 12 isoform X6

  37. XM_047436283.1 → XP_047292239.1  cyclin-dependent kinase 12 isoform X6

  38. XM_047436280.1 → XP_047292236.1  cyclin-dependent kinase 12 isoform X6

  39. XM_047436281.1 → XP_047292237.1  cyclin-dependent kinase 12 isoform X6

  40. XM_047436284.1 → XP_047292240.1  cyclin-dependent kinase 12 isoform X6

  41. XM_047436285.1 → XP_047292241.1  cyclin-dependent kinase 12 isoform X6

  42. XM_047436286.1 → XP_047292242.1  cyclin-dependent kinase 12 isoform X6

  43. XM_047436290.1 → XP_047292246.1  cyclin-dependent kinase 12 isoform X8

  44. XM_017024753.3 → XP_016880242.1  cyclin-dependent kinase 12 isoform X8

    UniProtKB/TrEMBL
    J3QSD7

  45. XM_047436292.1 → XP_047292248.1  cyclin-dependent kinase 12 isoform X8

  46. XM_047436291.1 → XP_047292247.1  cyclin-dependent kinase 12 isoform X8

    Related
    ENSP00000464641.1, ENST00000584632.5

  47. XM_005257456.5 → XP_005257513.1  cyclin-dependent kinase 12 isoform X1

    UniProtKB/TrEMBL
    J3QSD7
    Conserved Domains (2) summary
    smart00220
    Location:726 → 1019
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:718 → 1019
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  48. XM_047436253.1 → XP_047292209.1  cyclin-dependent kinase 12 isoform X2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    40325392..40431128
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054316455.1 → XP_054172430.1  cyclin-dependent kinase 12 isoform X3

  2. XM_054316463.1 → XP_054172438.1  cyclin-dependent kinase 12 isoform X3

  3. XM_054316462.1 → XP_054172437.1  cyclin-dependent kinase 12 isoform X3

  4. XM_054316454.1 → XP_054172429.1  cyclin-dependent kinase 12 isoform X3

  5. XM_054316453.1 → XP_054172428.1  cyclin-dependent kinase 12 isoform X3

  6. XM_054316458.1 → XP_054172433.1  cyclin-dependent kinase 12 isoform X3

  7. XM_054316451.1 → XP_054172426.1  cyclin-dependent kinase 12 isoform X3

  8. XM_054316452.1 → XP_054172427.1  cyclin-dependent kinase 12 isoform X3

  9. XM_054316459.1 → XP_054172434.1  cyclin-dependent kinase 12 isoform X3

  10. XM_054316457.1 → XP_054172432.1  cyclin-dependent kinase 12 isoform X3

  11. XM_054316460.1 → XP_054172435.1  cyclin-dependent kinase 12 isoform X3

  12. XM_054316461.1 → XP_054172436.1  cyclin-dependent kinase 12 isoform X3

  13. XM_054316456.1 → XP_054172431.1  cyclin-dependent kinase 12 isoform X3

  14. XM_054316479.1 → XP_054172454.1  cyclin-dependent kinase 12 isoform X5

  15. XM_054316469.1 → XP_054172444.1  cyclin-dependent kinase 12 isoform X5

  16. XM_054316478.1 → XP_054172453.1  cyclin-dependent kinase 12 isoform X5

  17. XM_054316470.1 → XP_054172445.1  cyclin-dependent kinase 12 isoform X5

  18. XM_054316467.1 → XP_054172442.1  cyclin-dependent kinase 12 isoform X5

  19. XM_054316468.1 → XP_054172443.1  cyclin-dependent kinase 12 isoform X5

  20. XM_054316472.1 → XP_054172447.1  cyclin-dependent kinase 12 isoform X5

  21. XM_054316474.1 → XP_054172449.1  cyclin-dependent kinase 12 isoform X5

  22. XM_054316476.1 → XP_054172451.1  cyclin-dependent kinase 12 isoform X5

  23. XM_054316477.1 → XP_054172452.1  cyclin-dependent kinase 12 isoform X5

  24. XM_054316475.1 → XP_054172450.1  cyclin-dependent kinase 12 isoform X5

  25. XM_054316480.1 → XP_054172455.1  cyclin-dependent kinase 12 isoform X5

  26. XM_054316471.1 → XP_054172446.1  cyclin-dependent kinase 12 isoform X5

  27. XM_054316473.1 → XP_054172448.1  cyclin-dependent kinase 12 isoform X5

  28. XM_054316489.1 → XP_054172464.1  cyclin-dependent kinase 12 isoform X7

    UniProtKB/TrEMBL
    H0YLT2

  29. XM_054316488.1 → XP_054172463.1  cyclin-dependent kinase 12 isoform X7

    UniProtKB/TrEMBL
    H0YLT2

  30. XM_054316490.1 → XP_054172465.1  cyclin-dependent kinase 12 isoform X7

    UniProtKB/TrEMBL
    H0YLT2

  31. XM_054316491.1 → XP_054172466.1  cyclin-dependent kinase 12 isoform X7

    UniProtKB/TrEMBL
    H0YLT2

  32. XM_054316496.1 → XP_054172471.1  cyclin-dependent kinase 12 isoform X9

  33. XM_054316464.1 → XP_054172439.1  cyclin-dependent kinase 12 isoform X4

  34. XM_054316466.1 → XP_054172441.1  cyclin-dependent kinase 12 isoform X4

  35. XM_054316465.1 → XP_054172440.1  cyclin-dependent kinase 12 isoform X4

  36. XM_054316483.1 → XP_054172458.1  cyclin-dependent kinase 12 isoform X6

  37. XM_054316484.1 → XP_054172459.1  cyclin-dependent kinase 12 isoform X6

  38. XM_054316481.1 → XP_054172456.1  cyclin-dependent kinase 12 isoform X6

  39. XM_054316482.1 → XP_054172457.1  cyclin-dependent kinase 12 isoform X6

  40. XM_054316485.1 → XP_054172460.1  cyclin-dependent kinase 12 isoform X6

  41. XM_054316486.1 → XP_054172461.1  cyclin-dependent kinase 12 isoform X6

  42. XM_054316487.1 → XP_054172462.1  cyclin-dependent kinase 12 isoform X6

  43. XM_054316492.1 → XP_054172467.1  cyclin-dependent kinase 12 isoform X8

  44. XM_054316493.1 → XP_054172468.1  cyclin-dependent kinase 12 isoform X8

  45. XM_054316495.1 → XP_054172470.1  cyclin-dependent kinase 12 isoform X8

  46. XM_054316494.1 → XP_054172469.1  cyclin-dependent kinase 12 isoform X8

  47. XM_054316449.1 → XP_054172424.1  cyclin-dependent kinase 12 isoform X1

  48. XM_054316450.1 → XP_054172425.1  cyclin-dependent kinase 12 isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9NYV4.2 GenPept UniProtKB/Swiss-Prot:Q9NYV4

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