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ZBTB7B zinc finger and BTB domain containing 7B [ Homo sapiens (human) ]

Gene ID: 51043, updated on 2-Nov-2024

Summary

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Official Symbol
ZBTB7Bprovided by HGNC
Official Full Name
zinc finger and BTB domain containing 7Bprovided by HGNC
Primary source
HGNC:HGNC:18668
See related
Ensembl:ENSG00000160685 MIM:607646; AllianceGenome:HGNC:18668
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
vGAF; CKROX; THPOK; ZFP67; ZBTB15; ZFP-67; c-KROX; hcKROX; ZNF857B
Summary
This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Expression
Broad expression in skin (RPKM 39.5), duodenum (RPKM 31.2) and 25 other tissues See more
Orthologs
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Genomic context

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See ZBTB7B in Genome Data Viewer
Location:
1q21.3
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (155001750..155018523)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (154140715..154157896)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (154975125..154990999)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:154958088-154958777 Neighboring gene flavin adenine dinucleotide synthetase 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:154971857-154972809 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1375 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1376 Neighboring gene lens epithelial protein Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1377 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1378 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1379 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:154977250-154977922 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:154980166-154980880 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:154982382-154983131 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:154984631-154985378 Neighboring gene melanoma risk locus-associated MPRA allelic enhancer 1:154989823 Neighboring gene DC-STAMP domain containing 2 Neighboring gene DC-STAMP domain containing 1 Neighboring gene DCST1 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1802

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Th inducing POZ-Kruppel Factor (ThPOK) is a key regulator of the immune response since the early steps of colorectal carcinogenesis. Mariani F, et al. PLoS One, 2013. PMID 23349906, Free PMC Article
  2. Transcriptional control of T-cell development. Naito T, et al. Int Immunol, 2011 Nov. PMID 21948191
  3. Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration. Ghayor C, et al. J Biol Chem, 2000 Sep 1. PMID 10856292
  4. Transcriptional and epigenetic regulation of CD4/CD8 lineage choice. Taniuchi I, et al. Adv Immunol, 2011. PMID 21762816
  5. Expanding roles for ThPOK in thymic development. Kappes DJ. Immunol Rev, 2010 Nov. PMID 20969593, Free PMC Article

See all (74) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ALDH1A1 promotes immune escape of tumor cells through ZBTB7B-glycolysis pathway.
    Title: ALDH1A1 promotes immune escape of tumor cells through ZBTB7B-glycolysis pathway.
  2. A novel high-risk subpopulation identified by CTSL and ZBTB7B in gastric cancer.
    Title: A novel high-risk subpopulation identified by CTSL and ZBTB7B in gastric cancer.
  3. Epigenetic DNA methylation of Zbtb7b regulates the population of double-positive CD4(+)CD8(+) T cells in ulcerative colitis.
    Title: Epigenetic DNA methylation of Zbtb7b regulates the population of double-positive CD4(+)CD8(+) T cells in ulcerative colitis.
  4. ThPOK transcriptionally inactivates TNFRSF12A to increase the proliferation of T cells with the involvement of the NF-kB pathway.
    Title: ThPOK transcriptionally inactivates TNFRSF12A to increase the proliferation of T cells with the involvement of the NF-kB pathway.
  5. Zbtb7a and Zbtb7b: Opening naive loci to reprogram ESCs.
    Title: Zbtb7a and Zbtb7b: Opening naïve loci to reprogram ESCs.
  6. Zbtb7b suppresses aseptic inflammation by regulating m(6)A modification of IL6 mRNA.
    Title: Zbtb7b suppresses aseptic inflammation by regulating m(6)A modification of IL6 mRNA.
  7. Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.
    Title: Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.
  8. In vitro, prolonged activation of naive CD4 T cells in presence of Th1 polarizing cytokines led to the acquisition of perforin-dependent cytotoxic activity. This process was dependent on the Th1 transcription factor Runx3 and was limited by the sustained expression of ThPOK.
    Title: The transcription factors Runx3 and ThPOK cross-regulate acquisition of cytotoxic function by human Th1 lymphocytes.
  9. Authors show that the transcription factor ThPOK binds cooperatively with NF-kappaB to NRCs and mediates their physical proximity with the IFNB1 gene via its ability to oligomerize when bound to DNA.
    Title: The Transcription Factor ThPOK Orchestrates Stochastic Interchromosomal Interactions Required for IFNB1 Virus-Inducible Gene Expression.
  10. a novel pathway by which TIP60 and ThPOK synergistically suppresses Eomes function and IFNgamma production, which could contribute to the regulation of inflammation.
    Title: 60-kDa Tat-interactive protein (TIP60) positively regulates Th-inducing POK (ThPOK)-mediated repression of eomesodermin in human CD4+ T cells.
Submit: New GeneRIF Correction See all GeneRIFs (21)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A novel common variant in DCST2 is associated with length in early life and height in adulthood.
EBI GWAS Catalog
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • DKFZp686G01254

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription repressor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables sequence-specific double-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in NK T cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in adaptive thermogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in ectoderm development TAS
Traceable Author Statement
more info
 PubMed 
involved_in lactation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in negative regulation of CD8-positive, alpha-beta T cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in negative regulation of NK T cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in negative regulation of T-helper 17 cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of gene expression IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of CD4-positive, alpha-beta T cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of SREBP signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of brown fat cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of cold-induced thermogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in positive regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of gene expression ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of insulin receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of interleukin-17 production ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to insulin ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in transcription by RNA polymerase II TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  

General protein information

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Preferred Names
zinc finger and BTB domain-containing protein 7B
Names
T-helper-inducing POZ/Krueppel-like factor
krueppel-related zinc finger protein cKrox
zinc finger and BTB domain containing 15
zinc finger protein 67 homolog
zinc finger protein 857B
zinc finger protein Th-POK

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252406.3 → NP_001239335.1  zinc finger and BTB domain-containing protein 7B isoform 2

    See identical proteins and their annotated locations for NP_001239335.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) represents the longest transcript and encodes the longer isoform (2).
    Source sequence(s)
    AI270090, AK304762, AL451085, BC012070, CV572166, DB241444
    Consensus CDS
    CCDS58030.1
    UniProtKB/TrEMBL
    A8K6F4
    Related
    ENSP00000406286.2, ENST00000417934.6
    Conserved Domains (3) summary
    sd00017
    Location:410 → 430
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18327
    Location:43 → 176
    BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)
    pfam13465
    Location:397 → 419
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001256455.2 → NP_001243384.1  zinc finger and BTB domain-containing protein 7B isoform 1

    See identical proteins and their annotated locations for NP_001243384.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks two alternate exons in the 5' UTR and 5' coding region, and uses a downstream in-frame start codon, comapred to variant 3. The encoded isoform (1) is shorter at the N-terminus, compared to isoform 2.
    Source sequence(s)
    AI270090, AL451085, BC012070, CV572166
    Consensus CDS
    CCDS1081.1
    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
    UniProtKB/TrEMBL
    A8K6F4
    Related
    ENSP00000438647.1, ENST00000535420.6
    Conserved Domains (4) summary
    COG5048
    Location:345 → 424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:376 → 396
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18327
    Location:9 → 142
    BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)
    pfam13465
    Location:363 → 385
    zf-H2C2_2; Zinc-finger double domain

  3. NM_001377451.1 → NP_001364380.1  zinc finger and BTB domain-containing protein 7B isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL451085
    Consensus CDS
    CCDS58030.1
    UniProtKB/TrEMBL
    A8K6F4
    Conserved Domains (3) summary
    sd00017
    Location:410 → 430
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18327
    Location:43 → 176
    BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)
    pfam13465
    Location:397 → 419
    zf-H2C2_2; Zinc-finger double domain

  4. NM_001377452.1 → NP_001364381.1  zinc finger and BTB domain-containing protein 7B isoform 1

    Status: REVIEWED

    Source sequence(s)
    AL451085
    Consensus CDS
    CCDS1081.1
    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
    UniProtKB/TrEMBL
    A8K6F4
    Conserved Domains (4) summary
    COG5048
    Location:345 → 424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:376 → 396
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18327
    Location:9 → 142
    BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)
    pfam13465
    Location:363 → 385
    zf-H2C2_2; Zinc-finger double domain

  5. NM_001377453.1 → NP_001364382.1  zinc finger and BTB domain-containing protein 7B isoform 1

    Status: REVIEWED

    Source sequence(s)
    AL451085
    Consensus CDS
    CCDS1081.1
    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
    UniProtKB/TrEMBL
    A8K6F4
    Related
    ENSP00000357411.3, ENST00000368426.3
    Conserved Domains (4) summary
    COG5048
    Location:345 → 424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:376 → 396
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18327
    Location:9 → 142
    BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)
    pfam13465
    Location:363 → 385
    zf-H2C2_2; Zinc-finger double domain

  6. NM_001377454.1 → NP_001364383.1  zinc finger and BTB domain-containing protein 7B isoform 1

    Status: REVIEWED

    Source sequence(s)
    AL451085
    Consensus CDS
    CCDS1081.1
    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
    UniProtKB/TrEMBL
    A8K6F4
    Conserved Domains (4) summary
    COG5048
    Location:345 → 424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:376 → 396
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18327
    Location:9 → 142
    BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)
    pfam13465
    Location:363 → 385
    zf-H2C2_2; Zinc-finger double domain

  7. NM_001377455.1 → NP_001364384.1  zinc finger and BTB domain-containing protein 7B isoform 1

    Status: REVIEWED

    Source sequence(s)
    AL451085
    Consensus CDS
    CCDS1081.1
    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
    UniProtKB/TrEMBL
    A8K6F4
    Conserved Domains (4) summary
    COG5048
    Location:345 → 424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:376 → 396
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18327
    Location:9 → 142
    BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)
    pfam13465
    Location:363 → 385
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    155001750..155018523
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047421851.1 → XP_047277807.1  zinc finger and BTB domain-containing protein 7B isoform X2

  2. XM_006711359.3 → XP_006711422.1  zinc finger and BTB domain-containing protein 7B isoform X5

    See identical proteins and their annotated locations for XP_006711422.1

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
    UniProtKB/TrEMBL
    A8K6F4
    Conserved Domains (4) summary
    COG5048
    Location:345 → 424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:376 → 396
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18327
    Location:9 → 142
    BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)
    pfam13465
    Location:363 → 385
    zf-H2C2_2; Zinc-finger double domain

  3. XM_047421865.1 → XP_047277821.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  4. XM_047421871.1 → XP_047277827.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
    Related
    ENSP00000292176.2, ENST00000292176.2

  5. XM_047421852.1 → XP_047277808.1  zinc finger and BTB domain-containing protein 7B isoform X3

  6. XM_047421858.1 → XP_047277814.1  zinc finger and BTB domain-containing protein 7B isoform X4

  7. XM_047421894.1 → XP_047277850.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  8. XM_011509599.3 → XP_011507901.1  zinc finger and BTB domain-containing protein 7B isoform X5

    See identical proteins and their annotated locations for XP_011507901.1

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
    UniProtKB/TrEMBL
    A8K6F4
    Conserved Domains (4) summary
    COG5048
    Location:345 → 424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:376 → 396
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18327
    Location:9 → 142
    BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)
    pfam13465
    Location:363 → 385
    zf-H2C2_2; Zinc-finger double domain

  9. XM_047421853.1 → XP_047277809.1  zinc finger and BTB domain-containing protein 7B isoform X4

  10. XM_047421876.1 → XP_047277832.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  11. XM_047421868.1 → XP_047277824.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  12. XM_047421854.1 → XP_047277810.1  zinc finger and BTB domain-containing protein 7B isoform X4

  13. XM_047421883.1 → XP_047277839.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  14. XM_017001399.2 → XP_016856888.1  zinc finger and BTB domain-containing protein 7B isoform X1

    UniProtKB/TrEMBL
    A8K6F4

  15. XM_006711356.4 → XP_006711419.1  zinc finger and BTB domain-containing protein 7B isoform X5

    See identical proteins and their annotated locations for XP_006711419.1

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
    UniProtKB/TrEMBL
    A8K6F4
    Conserved Domains (4) summary
    COG5048
    Location:345 → 424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:376 → 396
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18327
    Location:9 → 142
    BTB_POZ_ZBTB7B_ZBTB15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7B (ZBTB7B)
    pfam13465
    Location:363 → 385
    zf-H2C2_2; Zinc-finger double domain

  16. XM_047421863.1 → XP_047277819.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    154140715..154157896
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054336854.1 → XP_054192829.1  zinc finger and BTB domain-containing protein 7B isoform X2

  2. XM_054336857.1 → XP_054192832.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  3. XM_054336860.1 → XP_054192835.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  4. XM_054336862.1 → XP_054192837.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  5. XM_054336856.1 → XP_054192831.1  zinc finger and BTB domain-containing protein 7B isoform X4

  6. XM_054336859.1 → XP_054192834.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  7. XM_054336855.1 → XP_054192830.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  8. XM_054336863.1 → XP_054192838.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  9. XM_054336853.1 → XP_054192828.1  zinc finger and BTB domain-containing protein 7B isoform X1

  10. XM_054336861.1 → XP_054192836.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2

  11. XM_054336858.1 → XP_054192833.1  zinc finger and BTB domain-containing protein 7B isoform X5

    UniProtKB/Swiss-Prot
    B4E3K5, D3DV83, J3KQQ3, O15156, Q68DR2, Q96EP2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O15156.2 GenPept UniProtKB/Swiss-Prot:O15156

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