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Iqcf1 IQ motif containing F1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 503227, updated on 2-Nov-2024

Summary

Official Symbol
Iqcf1provided by RGD
Official Full Name
IQ motif containing F1provided by RGD
Primary source
RGD:1565640
See related
EnsemblRapid:ENSRNOG00000037289 AllianceGenome:RGD:1565640
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1565640
Summary
Predicted to enable calmodulin binding activity. Predicted to be involved in positive regulation of acrosome reaction and positive regulation of flagellated sperm motility involved in capacitation. Predicted to be active in acrosomal vesicle. Orthologous to human IQCF1 (IQ motif containing F1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 101.5) See more
Orthologs
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Genomic context

See Iqcf1 in Genome Data Viewer
Location:
8q32
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (116008081..116011950)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (107129462..107133242)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (115191919..115195599)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene poly(rC) binding protein 4 Neighboring gene G protein-coupled receptor 62 Neighboring gene poly (ADP-ribose) polymerase family, member 3 Neighboring gene ribosomal RNA processing 9, U3 small nucleolar RNA binding protein Neighboring gene IQ motif containing F5 Neighboring gene IQ motif containing F3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables calmodulin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calmodulin binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in acrosomal vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in acrosomal vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
IQ domain-containing protein F1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109361.1NP_001102831.1  IQ domain-containing protein F1

    See identical proteins and their annotated locations for NP_001102831.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473954
    UniProtKB/TrEMBL
    A6I2T9, D3ZLI2
    Related
    ENSRNOP00000053229.2, ENSRNOT00000056391.5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    116008081..116011950
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006243838.5XP_006243900.1  IQ domain-containing protein F1 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZZQ9
    Related
    ENSRNOP00000085269.1, ENSRNOT00000110544.2