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Ccdc38 coiled-coil domain containing 38 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500823, updated on 2-Nov-2024

Summary

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Official Symbol
Ccdc38provided by RGD
Official Full Name
coiled-coil domain containing 38provided by RGD
Primary source
RGD:1564046
See related
EnsemblRapid:ENSRNOG00000021892 AllianceGenome:RGD:1564046
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564046
Summary
Predicted to enable ubiquitin-modified histone reader activity. Predicted to be involved in acrosome assembly. Predicted to be located in several cellular components, including manchette; sperm flagellum; and sperm head. Predicted to be active in centrosome. Orthologous to human CCDC38 (coiled-coil domain containing 38). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 66.1), Liver (RPKM 24.1) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ccdc38 in Genome Data Viewer
Location:
7q13
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (29943046..30017512)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (28055883..28129938)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (34402861..34477750)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102553539 Neighboring gene leukotriene A4 hydrolase Neighboring gene histidine ammonia lyase Neighboring gene amidohydrolase domain containing 1 Neighboring gene small nuclear ribonucleoprotein polypeptide F Neighboring gene netrin 4 Neighboring gene ribosomal protein S21, pseudogene 5 Neighboring gene uncharacterized LOC134479662

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Inhibition by propionyl-coenzyme A of N-acetylglutamate synthetase in rat liver mitochondria. A possible explanation for hyperammonemia in propionic and methylmalonic acidemia. Coude FX, et al. J Clin Invest, 1979 Dec. PMID 500823, Free PMC Article
  2. Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. Firat-Karalar EN, et al. J Cell Sci, 2014 Oct 1. PMID 25074808, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ubiquitin-modified histone reader activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in acrosome assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of intraciliary anterograde transport ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of sperm flagellum assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in sperm flagellum assembly ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of spermatogenesis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in cilium ISO
Inferred from Sequence Orthology
more info
  
located_in manchette ISO
Inferred from Sequence Orthology
more info
  
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in sperm flagellum ISO
Inferred from Sequence Orthology
more info
  
located_in sperm head ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 38

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    29943046..30017512
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039080091.2 → XP_038936019.2  coiled-coil domain-containing protein 38 isoform X1

    UniProtKB/TrEMBL
    F1LUB9

  2. XM_063264412.1 → XP_063120482.1  coiled-coil domain-containing protein 38 isoform X4

  3. XM_063264410.1 → XP_063120480.1  coiled-coil domain-containing protein 38 isoform X3

  4. XM_063264413.1 → XP_063120483.1  coiled-coil domain-containing protein 38 isoform X5

  5. XM_063264408.1 → XP_063120478.1  coiled-coil domain-containing protein 38 isoform X2

    Related
    ENSRNOP00000102560.1, ENSRNOT00000170143.1

  6. XM_063264411.1 → XP_063120481.1  coiled-coil domain-containing protein 38 isoform X4

  7. XM_039080093.2 → XP_038936021.1  coiled-coil domain-containing protein 38 isoform X1

    UniProtKB/TrEMBL
    F1LUB9
    Related
    ENSRNOP00000031846.7, ENSRNOT00000030985.9
    Conserved Domains (1) summary
    pfam13863
    Location:197 → 315
    DUF4200; Domain of unknown function (DUF4200)

  8. XM_063264409.1 → XP_063120479.1  coiled-coil domain-containing protein 38 isoform X3

    Related
    ENSRNOP00000106576.1, ENSRNOT00000173930.1
Nucleotide Protein Strain
Heading Accession and Version

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Chemical Information
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Research Materials