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Gltpd2 glycolipid transfer protein domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 497943, updated on 17-Aug-2024

Summary

Official Symbol
Gltpd2provided by RGD
Official Full Name
glycolipid transfer protein domain containing 2provided by RGD
Primary source
RGD:1560459
See related
EnsemblRapid:ENSRNOG00000070553 AllianceGenome:RGD:1560459
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1560459
Summary
Predicted to enable ceramide 1-phosphate binding activity and ceramide 1-phosphate transfer activity. Predicted to be involved in ceramide transport and intermembrane lipid transfer. Predicted to be integral component of membrane. Predicted to be active in cytosol. Orthologous to human GLTPD2 (glycolipid transfer protein domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Liver (RPKM 351.3) and Lung (RPKM 15.8) See more
Orthologs
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Genomic context

See Gltpd2 in Genome Data Viewer
Location:
10q24
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55732199..55734974)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (55233563..55236125)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (57126127..57127783)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene C-X-C motif chemokine ligand 16 Neighboring gene zinc finger, MYND-type containing 15 Neighboring gene transmembrane 4 L six family member 5 Neighboring gene vitelline membrane outer layer 1 homolog Neighboring gene chromosome 10 C17orf114 homolog Neighboring gene proteasome 20S subunit beta 6

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ceramide 1-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ceramide 1-phosphate transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in ceramide 1-phosphate transport IEA
Inferred from Electronic Annotation
more info
 
involved_in ceramide transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermembrane lipid transfer IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
glycolipid transfer protein domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001115030.1NP_001108502.1  glycolipid transfer protein domain-containing protein 2

    See identical proteins and their annotated locations for NP_001108502.1

    Status: PROVISIONAL

    Source sequence(s)
    BC158886
    UniProtKB/TrEMBL
    A0A8I5Y8A9, B0BNN1
    Related
    ENSRNOP00000077871.1, ENSRNOT00000095770.2
    Conserved Domains (1) summary
    pfam08718
    Location:140290
    GLTP; Glycolipid transfer protein (GLTP)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    55732199..55734974
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086600.2XP_038942528.1  glycolipid transfer protein domain-containing protein 2 isoform X1