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penk.L proenkephalin L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 495184, updated on 4-Nov-2024

Summary

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Official Symbol
penk.L
Official Full Name
proenkephalin L homeolog
Primary source
Xenbase:XB-GENE-942765
Locus tag
XELAEV_18032039mg
See related
EnsemblRapid:ENSXLAG00005016924 AllianceGenome:Xenbase:XB-GENE-942765
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
penk; penk-b
Summary
Predicted to enable opioid peptide activity and opioid receptor binding activity. Predicted to act upstream of or within chemical synaptic transmission; neuropeptide signaling pathway; and sensory perception. Predicted to be located in several cellular components, including axon terminus; dendrite; and neuronal cell body. Human ortholog(s) of this gene implicated in overactive bladder syndrome. Orthologous to human PENK (proenkephalin). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See penk.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (123748887..123755265, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (116606132..116612510, complement)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 7 L homeolog Neighboring gene short chain dehydrogenase/reductase family 16C member 5 L homeolog Neighboring gene serine/threonine-protein kinase mig-15-like Neighboring gene 3'(2'), 5'-bisphosphate nucleotidase 2 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables opioid peptide activity IEA
Inferred from Electronic Annotation
more info
  
enables opioid receptor binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sensory perception IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in axon terminus IEA
Inferred from Electronic Annotation
more info
  
located_in dendrite IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
proenkephalin-A-B
Names
Proenkephalin-A-B
enkephalin a
proenkephalin A2
proenkephalin-A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094874.1 → NP_001088343.2  proenkephalin-A-B preproprotein

    Status: PROVISIONAL

    Source sequence(s)
    BC084407
    UniProtKB/TrEMBL
    A0A8J0PZX3, A0A974CQC1
    Related
    ENSXLAP00005049847.1, ENSXLAT00005050988.1
    Conserved Domains (1) summary
    pfam01160
    Location:28 → 73
    Opiods_neuropep; Vertebrate endogenous opioids neuropeptide

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    123748887..123755265 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P07194.1 GenPept UniProtKB/Swiss-Prot:P07194

Gene LinkOut

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