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GUSB glucuronidase beta [ Felis catus (domestic cat) ]

Gene ID: 493879, updated on 18-Sep-2024

Summary

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Official Symbol
GUSB
Official Full Name
glucuronidase beta
Primary source
VGNC:VGNC:80580
See related
EnsemblRapid:ENSFCTG00005013531
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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See GUSB in Genome Data Viewer
Location:
chromosome: E3
Exon count:
12
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) E3 NC_058383.1 (15998917..16012394)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) E3 NC_018738.3 (16116420..16129899)

Chromosome E3 - NC_058383.1Genomic Context describing neighboring genes Neighboring gene argininosuccinate lyase Neighboring gene U6 spliceosomal RNA Neighboring gene vitamin K epoxide reductase complex subunit 1 like 1 Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene uncharacterized LOC109495195

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular basis of feline beta-glucuronidase deficiency: an animal model of mucopolysaccharidosis VII. Fyfe JC, et al. Genomics, 1999 Jun 1. PMID 10366443
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables beta-glucuronidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-glucuronidase
NP_001009310.1
XP_023101971.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009310.1 → NP_001009310.1  beta-glucuronidase precursor

    See identical proteins and their annotated locations for NP_001009310.1

    Status: PROVISIONAL

    Source sequence(s)
    AF012423
    UniProtKB/Swiss-Prot
    O97524
    UniProtKB/TrEMBL
    M3W6S0
    Related
    ENSFCTP00005027043.1, ENSFCTT00005038613.1
    Conserved Domains (4) summary
    PRK10150
    Location:27 → 630
    PRK10150; beta-D-glucuronidase; Provisional
    pfam00703
    Location:225 → 326
    Glyco_hydro_2; Glycosyl hydrolases family 2
    pfam02836
    Location:328 → 630
    Glyco_hydro_2_C; Glycosyl hydrolases family 2, TIM barrel domain
    pfam02837
    Location:36 → 223
    Glyco_hydro_2_N; Glycosyl hydrolases family 2, sugar binding domain

RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058383.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    15998917..16012394
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023246203.1 → XP_023101971.1  beta-glucuronidase isoform X1

    Conserved Domains (1) summary
    cl27651
    Location:20 → 412
    Glyco_hydro_2; Glycosyl hydrolases family 2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O97524.1 GenPept UniProtKB/Swiss-Prot:O97524

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials