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kpna6 karyopherin alpha 6 (importin alpha 7) [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 493380, updated on 4-Nov-2024

Summary

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Official Symbol
kpna6provided by Xenbase
Official Full Name
karyopherin alpha 6 (importin alpha 7)provided by Xenbase
Primary source
Xenbase:XB-GENE-946491
See related
Ensembl:ENSXETG00000005242 AllianceGenome:Xenbase:XB-GENE-946491
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to act upstream of or within protein import into nucleus. Predicted to be located in cytoplasm. Predicted to be active in nucleoplasm. Orthologous to human KPNA6 (karyopherin subunit alpha 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See kpna6 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
16
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (86569308..86586267)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (82408290..82425266)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene KH domain containing, RNA binding, signal transduction associated 1 Neighboring gene transmembrane protein 39B Neighboring gene taxilin alpha Neighboring gene coiled-coil domain containing 28B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC79508

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables nuclear import signal receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nuclear import signal receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables nuclear localization sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in NLS-bearing protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein import into nucleus IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
importin subunit alpha-7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008017.1 → NP_001008018.1  importin subunit alpha-7

    See identical proteins and their annotated locations for NP_001008018.1

    Status: PROVISIONAL

    Source sequence(s)
    BC080896
    UniProtKB/TrEMBL
    F6VEJ8, Q642T8
    Related
    ENSXETP00000011450.4, ENSXETT00000011450.5
    Conserved Domains (2) summary
    COG5064
    Location:33 → 511
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:252 → 277
    ARM; armadillo repeat [structural motif]

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    86569308..86586267
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018091194.2 → XP_017946683.1  importin subunit alpha-7 isoform X1

    UniProtKB/TrEMBL
    F6VEJ8, Q642T8
    Conserved Domains (2) summary
    COG5064
    Location:33 → 511
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:252 → 277
    ARM; armadillo repeat [structural motif]

  2. XM_012956814.2 → XP_012812268.1  importin subunit alpha-7 isoform X1

    See identical proteins and their annotated locations for XP_012812268.1

    UniProtKB/TrEMBL
    F6VEJ8, Q642T8
    Conserved Domains (2) summary
    COG5064
    Location:33 → 511
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:252 → 277
    ARM; armadillo repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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