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ephb1 EPH receptor B1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 493336, updated on 4-Nov-2024

Summary

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Official Symbol
ephb1provided by Xenbase
Official Full Name
EPH receptor B1provided by Xenbase
Primary source
Xenbase:XB-GENE-488626
See related
Ensembl:ENSXETG00000013722 AllianceGenome:Xenbase:XB-GENE-488626
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
Xek
Summary
Predicted to enable ATP binding activity and ephrin receptor activity. Predicted to act upstream of or within cell surface receptor protein tyrosine kinase signaling pathway; nervous system development; and protein phosphorylation. Predicted to be located in dendrite and plasma membrane. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human EPHB1 (EPH receptor B1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See ephb1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
16
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 5 NC_030681.2 (130467998..130602913)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 5 NC_030681.1 (126818501..126953102)

Chromosome 5 - NC_030681.2Genomic Context describing neighboring genes Neighboring gene kyphoscoliosis peptidase Neighboring gene kyphoscoliosis peptidase Neighboring gene uncharacterized LOC105948528 Neighboring gene uncharacterized LOC116410954 Neighboring gene alpha-1,4-N-acetylglucosaminyltransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC89790

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ephrin receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in dendrite IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ephrin type-B receptor 1
Names
Elk-like kinase
Xenopus Elk-like kinase
XP_002935121.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030681.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    130467998..130602913
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002935075.4 → XP_002935121.2  ephrin type-B receptor 1

    UniProtKB/TrEMBL
    A0A6I8R958, F6ZV43
    Related
    ENSXETP00000077216.2, ENSXETT00000103641.2
    Conserved Domains (5) summary
    cd05065
    Location:617 → 885
    PTKc_EphR_B; Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors
    cd09551
    Location:911 → 978
    SAM_EPH-B1; SAM domain of EPH-B1 subfamily of tyrosine kinase receptors
    cd10476
    Location:23 → 198
    EphR_LBD_B1; Ligand Binding Domain of Ephrin type-B Receptor 1
    cd00063
    Location:420 → 528
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam14575
    Location:549 → 617
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001007964.1: Suppressed sequence

    Description
    NM_001007964.1: This RefSeq was temporarily suppressed because the CDS was partial.
Nucleotide Protein Strain
Heading Accession and Version

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